Åstrand M - Search Results

1

Model-based characterization of the relationship between dapagliflozin systemic exposure and HbA1c response in patients with type 1 diabetes mellitus.

Parkinson J, Tang W, Åstrand M, Melin J, Ekholm E, Hamrén B, Boulton DW. Parkinson J, et al. Among authors: astrand m. Diabetes Obes Metab. 2019 Jun;21(6):1381-1387. doi: 10.1111/dom.13664. Epub 2019 Mar 14. Diabetes Obes Metab. 2019. PMID: 30756462 Free PMC article. Clinical Trial.

2

Pharmacokinetic-pharmacodynamic modelling of platelet response to ticagrelor in stable coronary artery disease and prior myocardial infarction patients.

Åstrand M, Amilon C, Röshammar D, Himmelmann A, Angiolillo DJ, Storey RF, Gurbel PA, Bonaca MP, Hamrén B. Åstrand M, et al. Br J Clin Pharmacol. 2019 Feb;85(2):413-421. doi: 10.1111/bcp.13812. Epub 2018 Dec 18. Br J Clin Pharmacol. 2019. PMID: 30414387 Free PMC article.

3

Population Pharmacokinetics/Pharmacodynamics of Ticagrelor in Children with Sickle Cell Disease.

Amilon C, Niazi M, Berggren A, Åstrand M, Hamrén B. Amilon C, et al. Among authors: astrand m. Clin Pharmacokinet. 2019 Oct;58(10):1295-1307. doi: 10.1007/s40262-019-00758-0. Clin Pharmacokinet. 2019. PMID: 30972696 Clinical Trial.

4

Dose-Response Mixed Models for Repeated Measures - a New Method for Assessment of Dose-Response.

Wellhagen GJ, Hamrén B, Kjellsson MC, Åstrand M. Wellhagen GJ, et al. Among authors: astrand m. Pharm Res. 2020 Jul 31;37(8):157. doi: 10.1007/s11095-020-02882-0. Pharm Res. 2020. PMID: 32737604 Free PMC article.

5

Pharmacokinetics of Roxadustat: A Population Analysis of 2855 Dialysis- and Non-Dialysis-Dependent Patients with Chronic Kidney Disease.

Rekić D, Kerbusch-Herben V, Någård M, Chou J, Huang J, Bradley C, Åstrand M, Tannenbaum S, Hamrén B. Rekić D, et al. Among authors: astrand m. Clin Pharmacokinet. 2021 Jun;60(6):759-773. doi: 10.1007/s40262-020-00974-z. Epub 2021 Jan 24. Clin Pharmacokinet. 2021. PMID: 33486718 Clinical Trial.

6

Population Pharmacokinetic Modeling of Cotadutide: A Dual Agonist Peptide of Glucagon-Like Peptide and Glucagon Receptors Administered to Participants with Type II Diabetes Mellitus, Chronic Kidney Disease, Obesity and Non-Alcoholic Steatohepatitis.

Yu H, Åstrand M, Cheng J, Nitin K, Hamrén B, Khan AA. Yu H, et al. Among authors: astrand m. Clin Pharmacokinet. 2024 Feb;63(2):255-267. doi: 10.1007/s40262-023-01337-0. Epub 2024 Jan 18. Clin Pharmacokinet. 2024. PMID: 38236561

7

Population Pharmacodynamic Dose-Response Analysis of Serum Potassium Following Dosing with Sodium Zirconium Cyclosilicate.

Penland RC, Åstrand M, Boulton DW, Någård M. Penland RC, et al. Among authors: astrand m. Clin Pharmacokinet. 2024 Apr;63(4):551-560. doi: 10.1007/s40262-024-01360-9. Epub 2024 Mar 19. Clin Pharmacokinet. 2024. PMID: 38504082 Free PMC article. Clinical Trial.

8

From Plan to Pivot: How Model-Informed Drug Development Shaped the Dose Strategy of the Zibotentan/Dapagliflozin ZENITH Trials.

Mercier AK, Ueckert S, Sunnåker M, Hamrén B, Ambery P, Greasley PJ, Åstrand M. Mercier AK, et al. Among authors: astrand m. Clin Pharmacol Ther. 2024 Sep;116(3):653-664. doi: 10.1002/cpt.3362. Epub 2024 Jul 3. Clin Pharmacol Ther. 2024. PMID: 38961664

9

Effects of Zibotentan Alone and in Combination with Dapagliflozin on Fluid Retention in Patients with CKD.

Smeijer JD, Wasehuus VS, Dhaun N, Górriz JL, Soler MJ, Åstrand M, Mercier AK, Greasley PJ, Ambery P, Heerspink HJL. Smeijer JD, et al. Among authors: astrand m. J Am Soc Nephrol. 2024 Oct 1;35(10):1381-1390. doi: 10.1681/ASN.0000000000000436. Epub 2024 Jul 12. J Am Soc Nephrol. 2024. PMID: 39352861 Clinical Trial.

10

Zibotentan in combination with dapagliflozin compared with dapagliflozin in patients with chronic kidney disease (ZENITH-CKD): a multicentre, randomised, active-controlled, phase 2b, clinical trial.

Heerspink HJL, Kiyosue A, Wheeler DC, Lin M, Wijkmark E, Carlson G, Mercier AK, Åstrand M, Ueckert S, Greasley PJ, Ambery P. Heerspink HJL, et al. Among authors: astrand m. Lancet. 2023 Nov 25;402(10416):2004-2017. doi: 10.1016/S0140-6736(23)02230-4. Epub 2023 Nov 3. Lancet. 2023. PMID: 37931629 Clinical Trial.

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