Engineered botulinum neurotoxin B with improved binding to human receptors has enhanced efficacy in preclinical models.
Elliott M, Favre-Guilmard C, Liu SM, Maignel J, Masuyer G, Beard M, Boone C, Carré D, Kalinichev M, Lezmi S, Mir I, Nicoleau C, Palan S, Perier C, Raban E, Zhang S, Dong M, Stenmark P, Krupp J.
Elliott M, et al. Among authors: lezmi s.
Sci Adv. 2019 Jan 16;5(1):eaau7196. doi: 10.1126/sciadv.aau7196. eCollection 2019 Jan.
Sci Adv. 2019.
PMID: 30746458
Free PMC article.