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Measurement of J-Tpeakc along with QT-Interval Prolongation May Increase the Assay Sensitivity and Specificity for Predicting the Onset of Drug-Induced Torsade de Pointes: Experimental Evidences Based on Proarrhythmia Model Animals.
Goto A, Hagiwara-Nagasawa M, Kambayashi R, Chiba K, Izumi-Nakaseko H, Naito AT, Kanda Y, Sugiyama A. Goto A, et al. Among authors: kambayashi r. Cardiovasc Toxicol. 2019 Aug;19(4):357-364. doi: 10.1007/s12012-019-09506-z. Cardiovasc Toxicol. 2019. PMID: 30712162
Characterization of microminipig as a laboratory animal for safety pharmacology study by analyzing fluvoxamine-induced cardiovascular and dermatological adverse reactions.
Tanikawa Y, Hagiwara-Nagasawa M, Kambayashi R, Goto A, Chiba K, Kitta K, Hoshiai K, Izumi-Nakaseko H, Naito AT, Sugiyama A. Tanikawa Y, et al. Among authors: kambayashi r. Cardiovasc Toxicol. 2019 Oct;19(5):412-421. doi: 10.1007/s12012-019-09509-w. Cardiovasc Toxicol. 2019. PMID: 30734885
Dasatinib can Impair Left Ventricular Mechanical Function But May Lack Proarrhythmic Effect: A Proposal of Non-clinical Guidance for Predicting Clinical Cardiovascular Adverse Events of Tyrosine Kinase Inhibitors.
Izumi-Nakaseko H, Fujiyoshi M, Hagiwara-Nagasawa M, Goto A, Chiba K, Kambayashi R, Naito AT, Ando K, Kanda Y, Ishii I, Sugiyama A. Izumi-Nakaseko H, et al. Among authors: kambayashi r. Cardiovasc Toxicol. 2020 Feb;20(1):58-70. doi: 10.1007/s12012-019-09538-5. Cardiovasc Toxicol. 2020. PMID: 31280457
Analysis of electro-mechanical relationship in human iPS cell-derived cardiomyocytes sheets under proarrhythmic condition assessed by simultaneous field potential and motion vector recordings.
Sugiyama A, Hagiwara-Nagasawa M, Kambayashi R, Goto A, Chiba K, Naito AT, Kanda Y, Matsumoto A, Izumi-Nakaseko H. Sugiyama A, et al. Among authors: kambayashi r. J Pharmacol Sci. 2019 Aug;140(4):317-320. doi: 10.1016/j.jphs.2019.07.006. Epub 2019 Jul 19. J Pharmacol Sci. 2019. PMID: 31377016 Free article.
Pharmacological β-adrenoceptor blockade can augment torsadogenic action of IKr inhibitor: Comparison of proarrhythmic effects of d-sotalol and dl-sotalol in the chronic atrioventricular block dogs.
Goto A, Hagiwara-Nagasawa M, Chiba K, Kambayashi R, Nunoi Y, Izumi-Nakaseko H, Matsumoto A, Kanda Y, Sugiyama A. Goto A, et al. Among authors: kambayashi r. J Pharmacol Sci. 2019 Sep;141(1):86-89. doi: 10.1016/j.jphs.2019.09.009. Epub 2019 Sep 24. J Pharmacol Sci. 2019. PMID: 31636019 Free article.
How the Deuteration of Dronedarone Can Modify Its Cardiovascular Profile: In Vivo Characterization of Electropharmacological Effects of Poyendarone, a Deuterated Analogue of Dronedarone.
Kambayashi R, Hagiwara-Nagasawa M, Kondo Y, Yeo ZJ, Goto A, Chiba K, Nunoi Y, Izumi-Nakaseko H, Leow JWH, Venkatesan G, Matsumoto A, Chan ECY, Sugiyama A. Kambayashi R, et al. Cardiovasc Toxicol. 2020 Aug;20(4):339-350. doi: 10.1007/s12012-019-09559-0. Cardiovasc Toxicol. 2020. PMID: 31898152
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