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Hypoxic cancer-associated fibroblasts increase NCBP2-AS2/HIAR to promote endothelial sprouting through enhanced VEGF signaling.
Kugeratski FG, Atkinson SJ, Neilson LJ, Lilla S, Knight JRP, Serneels J, Juin A, Ismail S, Bryant DM, Markert EK, Machesky LM, Mazzone M, Sansom OJ, Zanivan S. Kugeratski FG, et al. Among authors: knight jrp. Sci Signal. 2019 Feb 5;12(567):eaan8247. doi: 10.1126/scisignal.aan8247. Sci Signal. 2019. PMID: 30723174 Free PMC article.
mTORC1-mediated translational elongation limits intestinal tumour initiation and growth.
Faller WJ, Jackson TJ, Knight JR, Ridgway RA, Jamieson T, Karim SA, Jones C, Radulescu S, Huels DJ, Myant KB, Dudek KM, Casey HA, Scopelliti A, Cordero JB, Vidal M, Pende M, Ryazanov AG, Sonenberg N, Meyuhas O, Hall MN, Bushell M, Willis AE, Sansom OJ. Faller WJ, et al. Nature. 2015 Jan 22;517(7535):497-500. doi: 10.1038/nature13896. Epub 2014 Nov 5. Nature. 2015. PMID: 25383520 Free PMC article.
Brf1 loss and not overexpression disrupts tissues homeostasis in the intestine, liver and pancreas.
Liko D, Mitchell L, Campbell KJ, Ridgway RA, Jones C, Dudek K, King A, Bryson S, Stevenson D, Blyth K, Strathdee D, Morton JP, Bird TG, Knight JRP, Willis AE, Sansom OJ. Liko D, et al. Among authors: knight jrp. Cell Death Differ. 2019 Dec;26(12):2535-2550. doi: 10.1038/s41418-019-0316-7. Epub 2019 Mar 11. Cell Death Differ. 2019. PMID: 30858608 Free PMC article.
Control of translation elongation in health and disease.
Knight JRP, Garland G, Pöyry T, Mead E, Vlahov N, Sfakianos A, Grosso S, De-Lima-Hedayioglu F, Mallucci GR, von der Haar T, Smales CM, Sansom OJ, Willis AE. Knight JRP, et al. Dis Model Mech. 2020 Mar 26;13(3):dmm043208. doi: 10.1242/dmm.043208. Dis Model Mech. 2020. PMID: 32298235 Free PMC article. Review.
The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer.
Najumudeen AK, Ceteci F, Fey SK, Hamm G, Steven RT, Hall H, Nikula CJ, Dexter A, Murta T, Race AM, Sumpton D, Vlahov N, Gay DM, Knight JRP, Jackstadt R, Leach JDG, Ridgway RA, Johnson ER, Nixon C, Hedley A, Gilroy K, Clark W, Malla SB, Dunne PD, Rodriguez-Blanco G, Critchlow SE, Mrowinska A, Malviya G, Solovyev D, Brown G, Lewis DY, Mackay GM, Strathdee D, Tardito S, Gottlieb E; CRUK Rosetta Grand Challenge Consortium; Takats Z, Barry ST, Goodwin RJA, Bunch J, Bushell M, Campbell AD, Sansom OJ. Najumudeen AK, et al. Among authors: knight jrp. Nat Genet. 2021 Jan;53(1):16-26. doi: 10.1038/s41588-020-00753-3. Epub 2021 Jan 7. Nat Genet. 2021. PMID: 33414552
Translation initiation in cancer at a glance.
Smith RCL, Kanellos G, Vlahov N, Alexandrou C, Willis AE, Knight JRP, Sansom OJ. Smith RCL, et al. Among authors: knight jrp. J Cell Sci. 2021 Jan 13;134(1):jcs248476. doi: 10.1242/jcs.248476. J Cell Sci. 2021. PMID: 33441326 Review.
Tuning protein synthesis for cancer therapy.
Knight JRP, Sansom OJ. Knight JRP, et al. Mol Cell Oncol. 2021 Feb 22;8(2):1884034. doi: 10.1080/23723556.2021.1884034. Mol Cell Oncol. 2021. PMID: 33855169 Free PMC article.
Correction to: Brf1 loss and not overexpression disrupts tissues homeostasis in the intestine, liver and pancreas.
Liko D, Mitchell L, Campbell KJ, Ridgway RA, Jones C, Dudek K, King A, Bryson S, Stevenson D, Blyth K, Strathdee D, Morton JP, Bird TG, Knight JRP, Willis AE, Sansom OJ. Liko D, et al. Among authors: knight jrp. Cell Death Differ. 2024 Sep;31(9):1235-1237. doi: 10.1038/s41418-024-01344-z. Cell Death Differ. 2024. PMID: 39095545 Free article. No abstract available.
30 results