Gamage SA - Search Results

1

Synthesis and Evaluation of Imidazo[1,2-a]pyridine Analogues of the ZSTK474 Class of Phosphatidylinositol 3-Kinase Inhibitors.

Gamage SA, Spicer JA, Tsang KY, O'Connor PD, Flanagan JU, Lee WJ, Dickson JMJ, Shepherd PR, Denny WA, Rewcastle GW. Gamage SA, et al. Chem Asian J. 2019 Apr 15;14(8):1249-1261. doi: 10.1002/asia.201801762. Epub 2019 Mar 12. Chem Asian J. 2019. PMID: 30714356

2

Synthesis and evaluation of unsymmetrical bis(arylcarboxamides) designed as topoisomerase-targeted anticancer drugs.

Spicer JA, Gamage SA, Finlay GJ, Denny WA. Spicer JA, et al. Among authors: gamage sa. Bioorg Med Chem. 2002 Jan;10(1):19-29. doi: 10.1016/s0968-0896(01)00249-8. Bioorg Med Chem. 2002. PMID: 11738603

3

Structure-activity relationships for pyrido-, imidazo-, pyrazolo-, pyrazino-, and pyrrolophenazinecarboxamides as topoisomerase-targeted anticancer agents.

Gamage SA, Spicer JA, Rewcastle GW, Milton J, Sohal S, Dangerfield W, Mistry P, Vicker N, Charlton PA, Denny WA. Gamage SA, et al. J Med Chem. 2002 Jan 31;45(3):740-3. doi: 10.1021/jm010330+. J Med Chem. 2002. PMID: 11806725

4

Structure-activity relationships of 1,2,4-benzotriazine 1,4-dioxides as hypoxia-selective analogues of tirapazamine.

Hay MP, Gamage SA, Kovacs MS, Pruijn FB, Anderson RF, Patterson AV, Wilson WR, Brown JM, Denny WA. Hay MP, et al. Among authors: gamage sa. J Med Chem. 2003 Jan 2;46(1):169-82. doi: 10.1021/jm020367+. J Med Chem. 2003. PMID: 12502371

5

Activation of 3-amino-1,2,4-benzotriazine 1,4-dioxide antitumor agents to oxidizing species following their one-electron reduction.

Anderson RF, Shinde SS, Hay MP, Gamage SA, Denny WA. Anderson RF, et al. Among authors: gamage sa. J Am Chem Soc. 2003 Jan 22;125(3):748-56. doi: 10.1021/ja0209363. J Am Chem Soc. 2003. PMID: 12526674

6

DNA-targeted 1,2,4-benzotriazine 1,4-dioxides: potent analogues of the hypoxia-selective cytotoxin tirapazamine.

Hay MP, Pruijn FB, Gamage SA, Liyanage HD, Kovacs MS, Patterson AV, Wilson WR, Brown JM, Denny WA. Hay MP, et al. Among authors: gamage sa. J Med Chem. 2004 Jan 15;47(2):475-88. doi: 10.1021/jm030399c. J Med Chem. 2004. PMID: 14711317

7

Oxidation of 2-deoxyribose by benzotriazinyl radicals of antitumor 3-amino-1,2,4-benzotriazine 1,4-dioxides.

Shinde SS, Anderson RF, Hay MP, Gamage SA, Denny WA. Shinde SS, et al. Among authors: gamage sa. J Am Chem Soc. 2004 Jun 30;126(25):7865-74. doi: 10.1021/ja048740l. J Am Chem Soc. 2004. PMID: 15212534

8

Radical properties governing the hypoxia-selective cytotoxicity of antitumor 3-amino-1,2,4-benzotriazine 1,4-dioxides.

Anderson RF, Shinde SS, Hay MP, Gamage SA, Denny WA. Anderson RF, et al. Among authors: gamage sa. Org Biomol Chem. 2005 Jun 7;3(11):2167-74. doi: 10.1039/b502586a. Epub 2005 Apr 29. Org Biomol Chem. 2005. PMID: 15917906

9

Phenazine-1-carboxamides: structure-cytotoxicity relationships for 9-substituents and changes in the H-bonding pattern of the cationic side chain.

Gamage SA, Rewcastle GW, Baguley BC, Charlton PA, Denny WA. Gamage SA, et al. Bioorg Med Chem. 2006 Feb 15;14(4):1160-8. doi: 10.1016/j.bmc.2005.09.032. Epub 2005 Oct 10. Bioorg Med Chem. 2006. PMID: 16216514

10

A new class of quinoline-based DNA hypomethylating agents reactivates tumor suppressor genes by blocking DNA methyltransferase 1 activity and inducing its degradation.

Datta J, Ghoshal K, Denny WA, Gamage SA, Brooke DG, Phiasivongsa P, Redkar S, Jacob ST. Datta J, et al. Among authors: gamage sa. Cancer Res. 2009 May 15;69(10):4277-85. doi: 10.1158/0008-5472.CAN-08-3669. Epub 2009 May 5. Cancer Res. 2009. Retraction in: Cancer Res. 2023 Dec 15;83(24):4180. doi: 10.1158/0008-5472.CAN-23-2366 PMID: 19417133 Free PMC article. Retracted.

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