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Durability of immune responses to mRNA booster vaccination against COVID-19.
Arunachalam PS, Lai L, Samaha H, Feng Y, Hu M, Hui HS, Wali B, Ellis M, Davis-Gardner ME, Huerta C, Bechnak K, Bechnak S, Lee M, Litvack MB, Losada C, Grifoni A, Sette A, Zarnitsyna VI, Rouphael N, Suthar MS, Pulendran B. Arunachalam PS, et al. J Clin Invest. 2023 May 15;133(10):e167955. doi: 10.1172/JCI167955. J Clin Invest. 2023. PMID: 36951954 Free PMC article.
Neutralization against BA.2.75.2, BQ.1.1, and XBB from mRNA Bivalent Booster.
Davis-Gardner ME, Lai L, Wali B, Samaha H, Solis D, Lee M, Porter-Morrison A, Hentenaar IT, Yamamoto F, Godbole S, Liu Y, Douek DC, Lee FE, Rouphael N, Moreno A, Pinsky BA, Suthar MS. Davis-Gardner ME, et al. N Engl J Med. 2023 Jan 12;388(2):183-185. doi: 10.1056/NEJMc2214293. Epub 2022 Dec 21. N Engl J Med. 2023. PMID: 36546661 Free PMC article. No abstract available.
Protection against SARS-CoV-2 Omicron BA.1 variant challenge in macaques by prime-boost vaccination with Ad26.COV2.S and SpFN.
Yu J, Thomas PV, McMahan K, Jacob-Dolan C, Liu J, He X, Hope D, Martinez EJ, Chen WH, Sciacca M, Hachmann NP, Lifton M, Miller J, Powers OC, Hall K, Wu C, Barrett J, Swafford I, Currier JR, King J, Corbitt C, Chang WC, Golub E, Rees PA, Peterson CE, Hajduczki A, Hussin E, Lange C, Gong H, Matyas GR, Rao M, Paquin-Proulx D, Gromowski GD, Lewis MG, Andersen H, Davis-Gardner M, Suthar MS, Michael NL, Bolton DL, Joyce MG, Modjarrad K, Barouch DH. Yu J, et al. Sci Adv. 2022 Nov 25;8(47):eade4433. doi: 10.1126/sciadv.ade4433. Epub 2022 Nov 23. Sci Adv. 2022. PMID: 36417525 Free PMC article.
eCD4-Ig Variants That More Potently Neutralize HIV-1.
Fetzer I, Gardner MR, Davis-Gardner ME, Prasad NR, Alfant B, Weber JA, Farzan M. Fetzer I, et al. J Virol. 2018 May 29;92(12):e02011-17. doi: 10.1128/JVI.02011-17. Print 2018 Jun 15. J Virol. 2018. PMID: 29593050 Free PMC article.
AAV-delivered eCD4-Ig protects rhesus macaques from high-dose SIVmac239 challenges.
Gardner MR, Fellinger CH, Kattenhorn LM, Davis-Gardner ME, Weber JA, Alfant B, Zhou AS, Prasad NR, Kondur HR, Newton WA, Weisgrau KL, Rakasz EG, Lifson JD, Gao G, Schultz-Darken N, Farzan M. Gardner MR, et al. Sci Transl Med. 2019 Jul 24;11(502):eaau5409. doi: 10.1126/scitranslmed.aau5409. Sci Transl Med. 2019. PMID: 31341061 Free PMC article.
Mutations from bat ACE2 orthologs markedly enhance ACE2-Fc neutralization of SARS-CoV-2.
Mou H, Quinlan BD, Peng H, Guo Y, Peng S, Zhang L, Davis-Gardner ME, Gardner MR, Crynen G, Voo ZX, Bailey CC, Alpert MD, Rader C, Choe H, Farzan M. Mou H, et al. bioRxiv [Preprint]. 2020 Jun 30:2020.06.29.178459. doi: 10.1101/2020.06.29.178459. bioRxiv. 2020. Update in: PLoS Pathog. 2021 Apr 9;17(4):e1009501. doi: 10.1371/journal.ppat.1009501 PMID: 32637954 Free PMC article. Updated. Preprint.
51 results