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Predictions of genotoxic potential, mode of action, molecular targets, and potency via a tiered multiflow® assay data analysis strategy.
Environ Mol Mutagen. 2019 Jul;60(6):513-533. doi: 10.1002/em.22274. Epub 2019 Feb 27.
Environ Mol Mutagen. 2019.
PMID: 30702769
Free PMC article.
Benchmark Dose Analysis of DNA Damage Biomarker Responses Provides Compound Potency and Adverse Outcome Pathway Information for the Topoisomerase II Inhibitor Class of Compounds.
Wheeldon RP, Bernacki DT, Dertinger SD, Bryce SM, Bemis JC, Johnson GE.
Wheeldon RP, et al.
Environ Mol Mutagen. 2020 Apr;61(4):396-407. doi: 10.1002/em.22360. Epub 2020 Feb 10.
Environ Mol Mutagen. 2020.
PMID: 31983063
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The use of benchmark dose uncertainty measurements for robust comparative potency analyses.
Wheeldon RP, Dertinger SD, Bryce SM, Bemis JC, Johnson GE.
Wheeldon RP, et al.
Environ Mol Mutagen. 2021 Mar;62(3):203-215. doi: 10.1002/em.22422. Epub 2021 Jan 18.
Environ Mol Mutagen. 2021.
PMID: 33428310
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Permitted daily exposure limits for noteworthy N-nitrosamines.
Johnson GE, Dobo K, Gollapudi B, Harvey J, Kenny J, Kenyon M, Lynch A, Minocherhomji S, Nicolette J, Thybaud V, Wheeldon R, Zeller A.
Johnson GE, et al.
Environ Mol Mutagen. 2021 Jun;62(5):293-305. doi: 10.1002/em.22446.
Environ Mol Mutagen. 2021.
PMID: 34089278
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