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Rationale and Design of the EMPA-TROPISM Trial (ATRU-4): Are the "Cardiac Benefits" of Empagliflozin Independent of its Hypoglycemic Activity?
Santos-Gallego CG, Garcia-Ropero A, Mancini D, Pinney SP, Contreras JP, Fergus I, Abascal V, Moreno P, Atallah-Lajam F, Tamler R, Lala A, Sanz J, Fuster V, Badimon JJ. Santos-Gallego CG, et al. Cardiovasc Drugs Ther. 2019 Feb;33(1):87-95. doi: 10.1007/s10557-018-06850-0. Cardiovasc Drugs Ther. 2019. PMID: 30675708
Randomized Trial of Empagliflozin in Nondiabetic Patients With Heart Failure and Reduced Ejection Fraction.
Santos-Gallego CG, Vargas-Delgado AP, Requena-Ibanez JA, Garcia-Ropero A, Mancini D, Pinney S, Macaluso F, Sartori S, Roque M, Sabatel-Perez F, Rodriguez-Cordero A, Zafar MU, Fergus I, Atallah-Lajam F, Contreras JP, Varley C, Moreno PR, Abascal VM, Lala A, Tamler R, Sanz J, Fuster V, Badimon JJ; EMPA-TROPISM (ATRU-4) Investigators. Santos-Gallego CG, et al. Among authors: garcia ropero a. J Am Coll Cardiol. 2021 Jan 26;77(3):243-255. doi: 10.1016/j.jacc.2020.11.008. Epub 2020 Nov 13. J Am Coll Cardiol. 2021. PMID: 33197559 Free article. Clinical Trial.
Metabolism of the failing heart and the impact of SGLT2 inhibitors.
Garcia-Ropero A, Santos-Gallego CG, Zafar MU, Badimon JJ. Garcia-Ropero A, et al. Expert Opin Drug Metab Toxicol. 2019 Apr;15(4):275-285. doi: 10.1080/17425255.2019.1588886. Epub 2019 Mar 11. Expert Opin Drug Metab Toxicol. 2019. PMID: 30822172 Review.
Empagliflozin Ameliorates Diastolic Dysfunction and Left Ventricular Fibrosis/Stiffness in Nondiabetic Heart Failure: A Multimodality Study.
Santos-Gallego CG, Requena-Ibanez JA, San Antonio R, Garcia-Ropero A, Ishikawa K, Watanabe S, Picatoste B, Vargas-Delgado AP, Flores-Umanzor EJ, Sanz J, Fuster V, Badimon JJ. Santos-Gallego CG, et al. Among authors: garcia ropero a. JACC Cardiovasc Imaging. 2021 Feb;14(2):393-407. doi: 10.1016/j.jcmg.2020.07.042. Epub 2020 Oct 29. JACC Cardiovasc Imaging. 2021. PMID: 33129742 Free article.
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