Chen X - Search Results

1

How does the novel T315L mutation of breakpoint cluster region-abelson (BCR-ABL) kinase confer resistance to ponatinib: a comparative molecular dynamics simulation study.

Zhang H, He X, Ni D, Mou L, Chen X, Lu S. Zhang H, et al. Among authors: chen x. J Biomol Struct Dyn. 2020 Jan;38(1):89-100. doi: 10.1080/07391102.2019.1567390. Epub 2019 Feb 5. J Biomol Struct Dyn. 2020. PMID: 30661457

2

The structural basis of the autoinhibition mechanism of glycogen synthase kinase 3β (GSK3β): molecular modeling and molecular dynamics simulation studies.

Mou L, Dou W, Meng G, Sun K, Chen X. Mou L, et al. Among authors: chen x. J Biomol Struct Dyn. 2020 Apr;38(6):1741-1750. doi: 10.1080/07391102.2019.1615988. Epub 2019 May 16. J Biomol Struct Dyn. 2020. PMID: 31057052

3

Markov State Models and Molecular Dynamics Simulations Provide Understanding of the Nucleotide-Dependent Dimerization-Based Activation of LRRK2 ROC Domain.

Li X, Qi Z, Ni D, Lu S, Chen L, Chen X. Li X, et al. Among authors: chen l, chen x. Molecules. 2021 Sep 17;26(18):5647. doi: 10.3390/molecules26185647. Molecules. 2021. PMID: 34577121 Free PMC article.

4

Deciphering the Mechanism of Gilteritinib Overcoming Lorlatinib Resistance to the Double Mutant I1171N/F1174I in Anaplastic Lymphoma Kinase.

Liang S, Wang Q, Qi X, Liu Y, Li G, Lu S, Mou L, Chen X. Liang S, et al. Among authors: chen x. Front Cell Dev Biol. 2021 Dec 23;9:808864. doi: 10.3389/fcell.2021.808864. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 35004700 Free PMC article.

5

Comparative efficacy of second-generation androgen receptor inhibitors for treating prostate cancer: A systematic review and network meta-analysis.

Chen X, Wang Q, Pan Y, Wang S, Li Y, Zhang H, Xu M, Zhou H, Liu X. Chen X, et al. Front Endocrinol (Lausanne). 2023 Mar 9;14:1134719. doi: 10.3389/fendo.2023.1134719. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 36967752 Free PMC article. Review.

6

Structural and energetic insights into the selective inhibition of PKMYT1 against WEE1.

Qi X, Li G, Liu J, Mou L, Zhang Y, Guo S, Chen X, Li W. Qi X, et al. Among authors: chen x. J Biomol Struct Dyn. 2024 Apr;42(6):3010-3018. doi: 10.1080/07391102.2023.2225106. Epub 2023 Jun 22. J Biomol Struct Dyn. 2024. PMID: 37345529

7

Stereo-selectivity of enantiomeric inhibitors to ubiquitin-specific protease 7 (USP7) dissected by molecular docking, molecular dynamics simulations, and binding free energy calculations.

Zhang Y, Dou W, Zhao Z, Li G, Li C, Chen X, Mou L. Zhang Y, et al. Among authors: chen x. Mol Divers. 2024 Sep 19. doi: 10.1007/s11030-024-10948-z. Online ahead of print. Mol Divers. 2024. PMID: 39298085

8

Comparative efficacy of olaparib in combination with or without novel antiandrogens for treating metastatic castration-resistant prostate cancer.

Chen X, Pan Y, Wang Q, Ren C, Li M, Hao X, Xie L, Liu X. Chen X, et al. Front Endocrinol (Lausanne). 2023 Oct 31;14:1225033. doi: 10.3389/fendo.2023.1225033. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 38027160 Free PMC article.

9

The association of various physical activities with erectile dysfunction: NHANES 2001-2004.

Zhou H, Xu M, Xu Z, Li M, Ren C, Chen X, Liu X. Zhou H, et al. Among authors: chen x. Sex Med. 2023 Jul 25;11(3):qfad036. doi: 10.1093/sexmed/qfad036. eCollection 2023 Jun. Sex Med. 2023. PMID: 37502219 Free PMC article.

10

Efficacy and toxicity of immune checkpoint inhibitors combination therapy for advanced renal cell carcinoma: a systematic review and network meta-analysis.

Chen X, Xu Z, Wu C, Xie L, Wang P, Liu X. Chen X, et al. Front Immunol. 2024 Feb 8;15:1255577. doi: 10.3389/fimmu.2024.1255577. eCollection 2024. Front Immunol. 2024. PMID: 38390328 Free PMC article.

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