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PVRIG and PVRL2 Are Induced in Cancer and Inhibit CD8+ T-cell Function.
Whelan S, Ophir E, Kotturi MF, Levy O, Ganguly S, Leung L, Vaknin I, Kumar S, Dassa L, Hansen K, Bernados D, Murter B, Soni A, Taube JM, Fader AN, Wang TL, Shih IM, White M, Pardoll DM, Liang SC. Whelan S, et al. Among authors: vaknin i. Cancer Immunol Res. 2019 Feb;7(2):257-268. doi: 10.1158/2326-6066.CIR-18-0442. Epub 2019 Jan 18. Cancer Immunol Res. 2019. PMID: 30659054 Free PMC article.
Mouse PVRIG Has CD8+ T Cell-Specific Coinhibitory Functions and Dampens Antitumor Immunity.
Murter B, Pan X, Ophir E, Alteber Z, Azulay M, Sen R, Levy O, Dassa L, Vaknin I, Fridman-Kfir T, Salomon R, Ravet A, Tam A, Levin D, Vaknin Y, Tatirovsky E, Machlenkin A, Pardoll D, Ganguly S. Murter B, et al. Among authors: vaknin i, vaknin y. Cancer Immunol Res. 2019 Feb;7(2):244-256. doi: 10.1158/2326-6066.CIR-18-0460. Epub 2019 Jan 18. Cancer Immunol Res. 2019. PMID: 30659055 Free PMC article.
Characterization of BAY 1905254, an Immune Checkpoint Inhibitor Targeting the Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2).
Huetter J, Gritzan U, Gutcher I, Doecke WD, Luetke-Eversloh MV, Golfier S, Roider HG, Frisk AL, Hunter J, Pow A, Drake A, Levine Z, Levy O, Azulay M, Barbiro I, Cojocaru G, Vaknin I, Kreft B, Roese L. Huetter J, et al. Among authors: vaknin i. Cancer Immunol Res. 2020 Jul;8(7):895-911. doi: 10.1158/2326-6066.CIR-19-0321. Epub 2020 Apr 20. Cancer Immunol Res. 2020. PMID: 32312711
ILDR2 Is a Novel B7-like Protein That Negatively Regulates T Cell Responses.
Hecht I, Toporik A, Podojil JR, Vaknin I, Cojocaru G, Oren A, Aizman E, Liang SC, Leung L, Dicken Y, Novik A, Marbach-Bar N, Elmesmari A, Tange C, Gilmour A, McIntyre D, Kurowska-Stolarska M, McNamee K, Leitner J, Greenwald S, Dassa L, Levine Z, Steinberger P, Williams RO, Miller SD, McInnes IB, Neria E, Rotman G. Hecht I, et al. Among authors: vaknin i. J Immunol. 2018 Mar 15;200(6):2025-2037. doi: 10.4049/jimmunol.1700325. Epub 2018 Feb 5. J Immunol. 2018. PMID: 29431694 Free PMC article.
Neural precursor cells inhibit multiple inflammatory signals.
Fainstein N, Vaknin I, Einstein O, Zisman P, Ben Sasson SZ, Baniyash M, Ben-Hur T. Fainstein N, et al. Among authors: vaknin i. Mol Cell Neurosci. 2008 Nov;39(3):335-41. doi: 10.1016/j.mcn.2008.07.007. Epub 2008 Jul 22. Mol Cell Neurosci. 2008. PMID: 18692138
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