Zhang Z - Search Results

1

Emerging new roles of the lysosome and neuronal ceroid lipofuscinoses.

Mukherjee AB, Appu AP, Sadhukhan T, Casey S, Mondal A, Zhang Z, Bagh MB. Mukherjee AB, et al. Among authors: zhang z. Mol Neurodegener. 2019 Jan 16;14(1):4. doi: 10.1186/s13024-018-0300-6. Mol Neurodegener. 2019. PMID: 30651094 Free PMC article. Review.

2

Cln1 gene disruption in mice reveals a common pathogenic link between two of the most lethal childhood neurodegenerative lysosomal storage disorders.

Chandra G, Bagh MB, Peng S, Saha A, Sarkar C, Moralle M, Zhang Z, Mukherjee AB. Chandra G, et al. Among authors: zhang z. Hum Mol Genet. 2015 Oct 1;24(19):5416-32. doi: 10.1093/hmg/ddv266. Epub 2015 Jul 9. Hum Mol Genet. 2015. PMID: 26160911 Free PMC article.

3

Stop codon read-through with PTC124 induces palmitoyl-protein thioesterase-1 activity, reduces thioester load and suppresses apoptosis in cultured cells from INCL patients.

Sarkar C, Zhang Z, Mukherjee AB. Sarkar C, et al. Among authors: zhang z. Mol Genet Metab. 2011 Nov;104(3):338-45. doi: 10.1016/j.ymgme.2011.05.021. Epub 2011 Jun 13. Mol Genet Metab. 2011. PMID: 21704547 Free PMC article.

4

Palmitoyl-protein thioesterase-1 deficiency mediates the activation of the unfolded protein response and neuronal apoptosis in INCL.

Zhang Z, Lee YC, Kim SJ, Choi MS, Tsai PC, Xu Y, Xiao YJ, Zhang P, Heffer A, Mukherjee AB. Zhang Z, et al. Among authors: zhang p. Hum Mol Genet. 2006 Jan 15;15(2):337-46. doi: 10.1093/hmg/ddi451. Epub 2005 Dec 20. Hum Mol Genet. 2006. PMID: 16368712

5

Palmitoyl-protein thioesterase-1 deficiency leads to the activation of caspase-9 and contributes to rapid neurodegeneration in INCL.

Kim SJ, Zhang Z, Lee YC, Mukherjee AB. Kim SJ, et al. Among authors: zhang z. Hum Mol Genet. 2006 May 15;15(10):1580-6. doi: 10.1093/hmg/ddl078. Epub 2006 Mar 28. Hum Mol Genet. 2006. PMID: 16571600

6

Endoplasmic reticulum stress-induced caspase-4 activation mediates apoptosis and neurodegeneration in INCL.

Kim SJ, Zhang Z, Hitomi E, Lee YC, Mukherjee AB. Kim SJ, et al. Among authors: zhang z. Hum Mol Genet. 2006 Jun 1;15(11):1826-34. doi: 10.1093/hmg/ddl105. Epub 2006 Apr 27. Hum Mol Genet. 2006. PMID: 16644870

7

ER and oxidative stresses are common mediators of apoptosis in both neurodegenerative and non-neurodegenerative lysosomal storage disorders and are alleviated by chemical chaperones.

Wei H, Kim SJ, Zhang Z, Tsai PC, Wisniewski KE, Mukherjee AB. Wei H, et al. Among authors: zhang z. Hum Mol Genet. 2008 Feb 15;17(4):469-77. doi: 10.1093/hmg/ddm324. Epub 2007 Nov 7. Hum Mol Genet. 2008. PMID: 17989065

8

Palmitoyl protein thioesterase-1 deficiency impairs synaptic vesicle recycling at nerve terminals, contributing to neuropathology in humans and mice.

Kim SJ, Zhang Z, Sarkar C, Tsai PC, Lee YC, Dye L, Mukherjee AB. Kim SJ, et al. Among authors: zhang z. J Clin Invest. 2008 Sep;118(9):3075-86. doi: 10.1172/JCI33482. J Clin Invest. 2008. PMID: 18704195 Free PMC article.

9

RAGE signaling contributes to neuroinflammation in infantile neuronal ceroid lipofuscinosis.

Saha A, Kim SJ, Zhang Z, Lee YC, Sarkar C, Tsai PC, Mukherjee AB. Saha A, et al. Among authors: zhang z. FEBS Lett. 2008 Nov 12;582(27):3823-31. doi: 10.1016/j.febslet.2008.10.015. Epub 2008 Oct 21. FEBS Lett. 2008. PMID: 18948101 Free PMC article.

10

Children with infantile neuronal ceroid lipofuscinosis have an increased risk of hypothermia and bradycardia during anesthesia.

Miao N, Levin SW, Baker EH, Caruso RC, Zhang Z, Gropman A, Koziol D, Wesley R, Mukherjee AB, Quezado ZM. Miao N, et al. Among authors: zhang z. Anesth Analg. 2009 Aug;109(2):372-8. doi: 10.1213/ane.0b013e3181aa6e95. Anesth Analg. 2009. PMID: 19608805 Free PMC article.

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