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Cbs overdosage is necessary and sufficient to induce cognitive phenotypes in mouse models of Down syndrome and interacts genetically with Dyrk1a.
Hum Mol Genet. 2019 May 1;28(9):1561-1577. doi: 10.1093/hmg/ddy447.
Hum Mol Genet. 2019.
PMID: 30649339
Dosage of the Abcg1-U2af1 region modifies locomotor and cognitive deficits observed in the Tc1 mouse model of Down syndrome.
Marechal D, Lopes Pereira P, Duchon A, Herault Y.
Marechal D, et al. Among authors: lopes pereira p.
PLoS One. 2015 Feb 23;10(2):e0115302. doi: 10.1371/journal.pone.0115302. eCollection 2015.
PLoS One. 2015.
PMID: 25706610
Free PMC article.
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Developmental molecular and functional cerebellar alterations induced by PCP4/PEP19 overexpression: implications for Down syndrome.
Mouton-Liger F, Sahún I, Collin T, Lopes Pereira P, Masini D, Thomas S, Paly E, Luilier S, Même S, Jouhault Q, Bennaï S, Beloeil JC, Bizot JC, Hérault Y, Dierssen M, Créau N.
Mouton-Liger F, et al. Among authors: lopes pereira p.
Neurobiol Dis. 2014 Mar;63:92-106. doi: 10.1016/j.nbd.2013.11.016. Epub 2013 Nov 28.
Neurobiol Dis. 2014.
PMID: 24291518
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