Barnett GV - Search Results

1

Probing the Tryptophan Environment in Therapeutic Proteins: Implications for Higher Order Structure on Tryptophan Oxidation.

Barnett GV, Balakrishnan G, Chennamsetty N, Hoffman L, Bongers J, Tao L, Huang Y, Slaney T, Das TK, Leone A, Kar SR. Barnett GV, et al. J Pharm Sci. 2019 Jun;108(6):1944-1952. doi: 10.1016/j.xphs.2018.12.027. Epub 2019 Jan 11. J Pharm Sci. 2019. PMID: 30639740

2

Unique Impacts of Methionine Oxidation, Tryptophan Oxidation, and Asparagine Deamidation on Antibody Stability and Aggregation.

Alam ME, Slaney TR, Wu L, Das TK, Kar S, Barnett GV, Leone A, Tessier PM. Alam ME, et al. Among authors: barnett gv. J Pharm Sci. 2020 Jan;109(1):656-669. doi: 10.1016/j.xphs.2019.10.051. Epub 2019 Oct 31. J Pharm Sci. 2020. PMID: 31678251

3

Submicron Protein Particle Characterization using Resistive Pulse Sensing and Conventional Light Scattering Based Approaches.

Barnett GV, Perhacs JM, Das TK, Kar SR. Barnett GV, et al. Pharm Res. 2018 Feb 8;35(3):58. doi: 10.1007/s11095-017-2306-0. Pharm Res. 2018. PMID: 29423663

4

Detection and Identification of the Vibrational Markers for the Quantification of Methionine Oxidation in Therapeutic Proteins.

Balakrishnan G, Barnett GV, Kar SR, Das TK. Balakrishnan G, et al. Among authors: barnett gv. Anal Chem. 2018 Jun 5;90(11):6959-6966. doi: 10.1021/acs.analchem.8b01238. Epub 2018 May 17. Anal Chem. 2018. PMID: 29741878

5

Enhanced Precision of Circular Dichroism Spectral Measurements Permits Detection of Subtle Higher Order Structural Changes in Therapeutic Proteins.

Barnett GV, Balakrishnan G, Chennamsetty N, Meengs B, Meyer J, Bongers J, Ludwig R, Tao L, Das TK, Leone A, Kar SR. Barnett GV, et al. J Pharm Sci. 2018 Oct;107(10):2559-2569. doi: 10.1016/j.xphs.2018.06.007. Epub 2018 Jun 18. J Pharm Sci. 2018. PMID: 29913140

6

Interference from Proteins and Surfactants on Particle Size Distributions Measured by Nanoparticle Tracking Analysis (NTA).

Bai K, Barnett GV, Kar SR, Das TK. Bai K, et al. Among authors: barnett gv. Pharm Res. 2017 Apr;34(4):800-808. doi: 10.1007/s11095-017-2109-3. Epub 2017 Feb 2. Pharm Res. 2017. PMID: 28155075

7

Deamidation Can Compromise Antibody Colloidal Stability and Enhance Aggregation in a pH-Dependent Manner.

Alam ME, Barnett GV, Slaney TR, Starr CG, Das TK, Tessier PM. Alam ME, et al. Among authors: barnett gv. Mol Pharm. 2019 May 6;16(5):1939-1949. doi: 10.1021/acs.molpharmaceut.8b01311. Epub 2019 Apr 16. Mol Pharm. 2019. PMID: 30916563

8

Protection of therapeutic antibodies from visible light induced degradation: Use safe light in manufacturing and storage.

Du C, Barnett G, Borwankar A, Lewandowski A, Singh N, Ghose S, Borys M, Li ZJ. Du C, et al. Eur J Pharm Biopharm. 2018 Jun;127:37-43. doi: 10.1016/j.ejpb.2018.02.007. Epub 2018 Feb 7. Eur J Pharm Biopharm. 2018. PMID: 29427628

9

Acetate- and Citrate-Specific Ion Effects on Unfolding and Temperature-Dependent Aggregation Rates of Anti-Streptavidin IgG1.

Barnett GV, Razinkov VI, Kerwin BA, Hillsley A, Roberts CJ. Barnett GV, et al. J Pharm Sci. 2016 Mar;105(3):1066-73. doi: 10.1016/j.xphs.2015.12.017. Epub 2016 Feb 3. J Pharm Sci. 2016. PMID: 26886346

10

Therapeutic protein purity and fragmented species characterization by capillary electrophoresis sodium dodecyl sulfate using systematic hybrid cleavage and forced degradation.

Duhamel L, Gu Y, Barnett G, Tao Y, Voronov S, Ding J, Mussa N, Li ZJ. Duhamel L, et al. Anal Bioanal Chem. 2019 Aug;411(21):5617-5629. doi: 10.1007/s00216-019-01942-8. Epub 2019 Jun 18. Anal Bioanal Chem. 2019. PMID: 31214752

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