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Discovery of 2-(cyclopropanecarboxamido)-N-(5-((1-(4-fluorobenzyl)piperidin-4-yl)methoxy)pyridin-3-yl)isonicotinamide as a potent dual AChE/GSK3β inhibitor for the treatment of Alzheimer's disease: Significantly increasing the level of acetylcholine in the brain without affecting that in intestine.
Jiang X, Liu C, Zou M, Xie H, Lin T, Lyu W, Xu J, Li Y, Feng F, Sun H, Liu W. Jiang X, et al. Among authors: xu j. Eur J Med Chem. 2021 Nov 5;223:113663. doi: 10.1016/j.ejmech.2021.113663. Epub 2021 Jun 22. Eur J Med Chem. 2021. PMID: 34198150
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