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HLA-C downregulation by HIV-1 adapts to host HLA genotype.
Bachtel ND, Umviligihozo G, Pickering S, Mota TM, Liang H, Del Prete GQ, Chatterjee P, Lee GQ, Thomas R, Brockman MA, Neil S, Carrington M, Bwana B, Bangsberg DR, Martin JN, Kallas EG, Donini CS, Cerqueira NB, O'Doherty UT, Hahn BH, Jones RB, Brumme ZL, Nixon DF, Apps R. Bachtel ND, et al. Among authors: mota tm. PLoS Pathog. 2018 Sep 4;14(9):e1007257. doi: 10.1371/journal.ppat.1007257. eCollection 2018 Sep. PLoS Pathog. 2018. PMID: 30180214 Free PMC article.
Longitudinal HIV sequencing reveals reservoir expression leading to decay which is obscured by clonal expansion.
Pinzone MR, VanBelzen DJ, Weissman S, Bertuccio MP, Cannon L, Venanzi-Rullo E, Migueles S, Jones RB, Mota T, Joseph SB, Groen K, Pasternak AO, Hwang WT, Sherman B, Vourekas A, Nunnari G, O'Doherty U. Pinzone MR, et al. Among authors: mota t. Nat Commun. 2019 Feb 13;10(1):728. doi: 10.1038/s41467-019-08431-7. Nat Commun. 2019. PMID: 30760706 Free PMC article.
Have Cells Harboring the HIV Reservoir Been Immunoedited?
Huang SH, McCann CD, Mota TM, Wang C, Lipkin SM, Jones RB. Huang SH, et al. Front Immunol. 2019 Aug 6;10:1842. doi: 10.3389/fimmu.2019.01842. eCollection 2019. Front Immunol. 2019. PMID: 31447850 Free PMC article.
BCL-2 antagonism sensitizes cytotoxic T cell-resistant HIV reservoirs to elimination ex vivo.
Ren Y, Huang SH, Patel S, Alberto WDC, Magat D, Ahimovic D, Macedo AB, Durga R, Chan D, Zale E, Mota TM, Truong R, Rohwetter T, McCann CD, Kovacs CM, Benko E, Wimpelberg A, Cannon C, Hardy WD, Bosque A, Bollard CM, Jones RB. Ren Y, et al. Among authors: mota tm. J Clin Invest. 2020 May 1;130(5):2542-2559. doi: 10.1172/JCI132374. J Clin Invest. 2020. PMID: 32027622 Free PMC article.
Integrated Assessment of Viral Transcription, Antigen Presentation, and CD8+ T Cell Function Reveals Multiple Limitations of Class I-Selective Histone Deacetylase Inhibitors during HIV-1 Latency Reversal.
Mota TM, McCann CD, Danesh A, Huang SH, Magat DB, Ren Y, Leyre L, Bui TD, Rohwetter TM, Kovacs CM, Benko E, MacLaren L, Wimpelberg A, Cannon CM, Hardy WD, Safrit JT, Jones RB. Mota TM, et al. J Virol. 2020 Apr 16;94(9):e01845-19. doi: 10.1128/JVI.01845-19. Print 2020 Apr 16. J Virol. 2020. PMID: 32051267 Free PMC article.
Immunological approaches to HIV cure.
Ward AR, Mota TM, Jones RB. Ward AR, et al. Semin Immunol. 2021 Jan;51:101412. doi: 10.1016/j.smim.2020.101412. Epub 2020 Sep 24. Semin Immunol. 2021. PMID: 32981836 Free article. Review.
186 results