Lu H - Search Results

1

Activation of EGFR-DNA-PKcs pathway by IGFBP2 protects esophageal adenocarcinoma cells from acidic bile salts-induced DNA damage.

Zhou Z, Lu H, Zhu S, Gomaa A, Chen Z, Yan J, Washington K, El-Rifai W, Dang C, Peng D. Zhou Z, et al. Among authors: lu h. J Exp Clin Cancer Res. 2019 Jan 9;38(1):13. doi: 10.1186/s13046-018-1021-y. J Exp Clin Cancer Res. 2019. PMID: 30626422 Free PMC article.

2

Helicobacter pylori-induced miR-135b-5p promotes cisplatin resistance in gastric cancer.

Shao L, Chen Z, Soutto M, Zhu S, Lu H, Romero-Gallo J, Peek R, Zhang S, El-Rifai W. Shao L, et al. Among authors: lu h. FASEB J. 2019 Jan;33(1):264-274. doi: 10.1096/fj.201701456RR. Epub 2018 Jul 9. FASEB J. 2019. PMID: 29985646 Free PMC article.

Our results uncovered a mechanistic link between H. pylori infection and miR-135b-5p-KLF4, suggesting that targeting miR-135b-5p could be a potential therapeutic approach to circumvent resistance to cisplatin.-Shao, L., Chen, Z., Soutto, M., Zhu, S., Lu, H., …

Our results uncovered a mechanistic link between H. pylori infection and miR-135b-5p-KLF4, suggesting that targeting miR-135b-5p coul …

3

Exposure of Barrett's and esophageal adenocarcinoma cells to bile acids activates EGFR-STAT3 signaling axis via induction of APE1.

Bhat AA, Lu H, Soutto M, Capobianco A, Rai P, Zaika A, El-Rifai W. Bhat AA, et al. Among authors: lu h. Oncogene. 2018 Nov;37(46):6011-6024. doi: 10.1038/s41388-018-0388-8. Epub 2018 Jul 10. Oncogene. 2018. PMID: 29991802 Free PMC article.

4

TFF1 antagonizes TIMP-1 mediated proliferative functions in gastric cancer.

Omar OM, Soutto M, Bhat NS, Bhat AA, Lu H, Chen Z, El-Rifai W. Omar OM, et al. Among authors: lu h. Mol Carcinog. 2018 Nov;57(11):1577-1587. doi: 10.1002/mc.22880. Epub 2018 Aug 14. Mol Carcinog. 2018. PMID: 30035371

5

NRF2 antioxidant response protects against acidic bile salts-induced oxidative stress and DNA damage in esophageal cells.

Peng D, Lu H, Zhu S, Zhou Z, Hu T, Chen Z, Zaika A, El-Rifai W. Peng D, et al. Among authors: lu h. Cancer Lett. 2019 Aug 28;458:46-55. doi: 10.1016/j.canlet.2019.05.031. Epub 2019 May 24. Cancer Lett. 2019. PMID: 31132430 Free PMC article.

6

APE1 Upregulates MMP-14 via Redox-Sensitive ARF6-Mediated Recycling to Promote Cell Invasion of Esophageal Adenocarcinoma.

Lu H, Bhat AA, Peng D, Chen Z, Zhu S, Hong J, Maacha S, Yan J, Robbins DJ, Washington MK, Belkhiri A, El-Rifai W. Lu H, et al. Cancer Res. 2019 Sep 1;79(17):4426-4438. doi: 10.1158/0008-5472.CAN-19-0237. Epub 2019 Jul 15. Cancer Res. 2019. PMID: 31308045 Free PMC article.

7

PRDX2 protects against oxidative stress induced by H. pylori and promotes resistance to cisplatin in gastric cancer.

Wang S, Chen Z, Zhu S, Lu H, Peng D, Soutto M, Naz H, Peek R Jr, Xu H, Zaika A, Xu Z, El-Rifai W. Wang S, et al. Among authors: lu h. Redox Biol. 2020 Jan;28:101319. doi: 10.1016/j.redox.2019.101319. Epub 2019 Sep 5. Redox Biol. 2020. PMID: 31536951 Free PMC article.

8

Silencing of miR490-3p by H. pylori activates DARPP-32 and induces resistance to gefitinib.

Zhu S, Khalafi S, Chen Z, Poveda J, Peng D, Lu H, Soutto M, Que J, Garcia-Buitrago M, Zaika A, El-Rifai W. Zhu S, et al. Among authors: lu h. Cancer Lett. 2020 Oct 28;491:87-96. doi: 10.1016/j.canlet.2020.07.014. Epub 2020 Jul 29. Cancer Lett. 2020. PMID: 32735911 Free PMC article.

9

N-MYC Downstream Regulated Gene 4 (NDRG4), a Frequent Downregulated Gene through DNA Hypermethylation, plays a Tumor Suppressive Role in Esophageal Adenocarcinoma.

Cao L, Hu T, Lu H, Peng D. Cao L, et al. Among authors: lu h. Cancers (Basel). 2020 Sep 10;12(9):2573. doi: 10.3390/cancers12092573. Cancers (Basel). 2020. PMID: 32927604 Free PMC article.

10

Activation of NRF2 by APE1/REF1 is redox-dependent in Barrett's related esophageal adenocarcinoma cells.

Sriramajayam K, Peng D, Lu H, Zhou S, Bhat N, McDonald OG, Que J, Zaika A, El-Rifai W. Sriramajayam K, et al. Among authors: lu h. Redox Biol. 2021 Jul;43:101970. doi: 10.1016/j.redox.2021.101970. Epub 2021 Apr 19. Redox Biol. 2021. PMID: 33887608 Free PMC article.

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