Shears SB - Search Results

1

Inhibition of Inositol Polyphosphate Kinases by Quercetin and Related Flavonoids: A Structure-Activity Analysis.

Gu C, Stashko MA, Puhl-Rubio AC, Chakraborty M, Chakraborty A, Frye SV, Pearce KH, Wang X, Shears SB, Wang H. Gu C, et al. Among authors: shears sb. J Med Chem. 2019 Feb 14;62(3):1443-1454. doi: 10.1021/acs.jmedchem.8b01593. Epub 2019 Jan 25. J Med Chem. 2019. PMID: 30624931 Free PMC article.

2

Purification and characterization of inositol-1,3,4-trisphosphate 5/6-kinase from rat liver using an inositol hexakisphosphate affinity column.

Abdullah M, Hughes PJ, Craxton A, Gigg R, Desai T, Marecek JF, Prestwich GD, Shears SB. Abdullah M, et al. Among authors: shears sb. J Biol Chem. 1992 Nov 5;267(31):22340-5. J Biol Chem. 1992. PMID: 1331051 Free article.

3

Inositol 1,3,4,5,6-pentakisphosphate and inositol hexakisphosphate inhibit inositol-1,3,4,5-tetrakisphosphate 3-phosphatase in rat parotid glands.

Hughes PJ, Shears SB. Hughes PJ, et al. Among authors: shears sb. J Biol Chem. 1990 Jun 15;265(17):9869-75. J Biol Chem. 1990. PMID: 2161845 Free article.

4

The regulation of the phosphorylation of inositol 1,3,4-trisphosphate in cell-free preparations and its relevance to the formation of inositol 1,3,4,6-tetrakisphosphate in agonist-stimulated rat parotid acinar cells.

Hughes PJ, Hughes AR, Putney JW Jr, Shears SB. Hughes PJ, et al. Among authors: shears sb. J Biol Chem. 1989 Nov 25;264(33):19871-8. J Biol Chem. 1989. PMID: 2555335 Free article.

5

Inositol 1,4,5,6-tetrakisphosphate is phosphorylated in rat liver by a 3-kinase that is distinct from inositol 1,4,5-trisphosphate 3-kinase.

Craxton A, Erneux C, Shears SB. Craxton A, et al. Among authors: shears sb. J Biol Chem. 1994 Feb 11;269(6):4337-42. J Biol Chem. 1994. PMID: 8308002 Free article.

6

Turnover of inositol polyphosphate pyrophosphates in pancreatoma cells.

Menniti FS, Miller RN, Putney JW Jr, Shears SB. Menniti FS, et al. Among authors: shears sb. J Biol Chem. 1993 Feb 25;268(6):3850-6. J Biol Chem. 1993. PMID: 8382679 Free article.

7

Properties of the inositol 3,4,5,6-tetrakisphosphate 1-kinase purified from rat liver. Regulation of enzyme activity by inositol 1,3,4-trisphosphate.

Tan Z, Bruzik KS, Shears SB. Tan Z, et al. Among authors: shears sb. J Biol Chem. 1997 Jan 24;272(4):2285-90. doi: 10.1074/jbc.272.4.2285. J Biol Chem. 1997. PMID: 8999935 Free article.

8

Inositol 1,3,4-trisphosphate acts in vivo as a specific regulator of cellular signaling by inositol 3,4,5,6-tetrakisphosphate.

Yang X, Rudolf M, Carew MA, Yoshida M, Nerreter V, Riley AM, Chung SK, Bruzik KS, Potter BV, Schultz C, Shears SB. Yang X, et al. Among authors: shears sb. J Biol Chem. 1999 Jul 2;274(27):18973-80. doi: 10.1074/jbc.274.27.18973. J Biol Chem. 1999. PMID: 10383396 Free article.

9

The transcriptional regulator, Arg82, is a hybrid kinase with both monophosphoinositol and diphosphoinositol polyphosphate synthase activity.

Zhang T, Caffrey JJ, Shears SB. Zhang T, et al. Among authors: shears sb. FEBS Lett. 2001 Apr 13;494(3):208-12. doi: 10.1016/s0014-5793(01)02351-1. FEBS Lett. 2001. PMID: 11311242 Free article.

10

Synthesis and biological activity of D- and L-chiro-inositol 2,3,4,5-tetrakisphosphate: design of a novel and potent inhibitor of Ins(3,4,5,6)P4 1-kinase/Ins(1,3,4)P3 5/6-kinase.

Liu C, Riley AM, Yang X, Shears SB, Potter BV. Liu C, et al. Among authors: shears sb. J Med Chem. 2001 Aug 30;44(18):2984-9. doi: 10.1021/jm000553k. J Med Chem. 2001. PMID: 11520207

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