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Identification of a BAZ2A-Bromodomain Hit Compound by Fragment Growing.
Dalle Vedove A, Cazzanelli G, Batiste L, Marchand JR, Spiliotopoulos D, Corsi J, D'Agostino VG, Caflisch A, Lolli G. Dalle Vedove A, et al. Among authors: lolli g. ACS Med Chem Lett. 2022 Aug 3;13(9):1434-1443. doi: 10.1021/acsmedchemlett.2c00173. eCollection 2022 Sep 8. ACS Med Chem Lett. 2022. PMID: 36105334 Free PMC article.
Identification of a BAZ2A Bromodomain Hit Compound by Fragment Joining.
Dalle Vedove A, Cazzanelli G, Corsi J, Sedykh M, D'Agostino VG, Caflisch A, Lolli G. Dalle Vedove A, et al. Among authors: lolli g. ACS Bio Med Chem Au. 2021 Dec 15;1(1):5-10. doi: 10.1021/acsbiomedchemau.1c00016. Epub 2021 Jul 7. ACS Bio Med Chem Au. 2021. PMID: 36147311 Free PMC article.
Small-Molecule Ebselen Binds to YTHDF Proteins Interfering with the Recognition of N 6-Methyladenosine-Modified RNAs.
Micaelli M, Dalle Vedove A, Cerofolini L, Vigna J, Sighel D, Zaccara S, Bonomo I, Poulentzas G, Rosatti EF, Cazzanelli G, Alunno L, Belli R, Peroni D, Dassi E, Murakami S, Jaffrey SR, Fragai M, Mancini I, Lolli G, Quattrone A, Provenzani A. Micaelli M, et al. Among authors: lolli g. ACS Pharmacol Transl Sci. 2022 Sep 14;5(10):872-891. doi: 10.1021/acsptsci.2c00008. eCollection 2022 Oct 14. ACS Pharmacol Transl Sci. 2022. PMID: 36268123 Free PMC article.
Reevaluation of bromodomain ligands targeting BAZ2A.
Cazzanelli G, Vedove AD, Parolin E, D'Agostino VG, Unzue A, Nevado C, Caflisch A, Lolli G. Cazzanelli G, et al. Among authors: lolli g. Protein Sci. 2023 Sep;32(9):e4752. doi: 10.1002/pro.4752. Protein Sci. 2023. PMID: 37574751 Free PMC article.
Pliability in the m6A-Binding Region Extends Druggability of YTH Domains.
Cazzanelli G, Dalle Vedove A, Spagnolli G, Terruzzi L, Colasurdo E, Boldrini A, Patsilinakos A, Sturlese M, Grottesi A, Biasini E, Provenzani A, Quattrone A, Lolli G. Cazzanelli G, et al. Among authors: lolli g. J Chem Inf Model. 2024 Mar 11;64(5):1682-1690. doi: 10.1021/acs.jcim.4c00051. Epub 2024 Feb 28. J Chem Inf Model. 2024. PMID: 38417111
191 results