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Preclinical assessment of MEK1/2 inhibitors for neurofibromatosis type 2-associated schwannomas reveals differences in efficacy and drug resistance development.
Fuse MA, Dinh CT, Vitte J, Kirkpatrick J, Mindos T, Plati SK, Young JI, Huang J, Carlstedt A, Franco MC, Brnjos K, Nagamoto J, Petrilli AM, Copik AJ, Soulakova JN, Bracho O, Yan D, Mittal R, Shen R, Telischi FF, Morrison H, Giovannini M, Liu XZ, Chang LS, Fernandez-Valle C. Fuse MA, et al. Among authors: chang ls. Neuro Oncol. 2019 Mar 18;21(4):486-497. doi: 10.1093/neuonc/noz002. Neuro Oncol. 2019. PMID: 30615146 Free PMC article.
Molecular studies of vestibular schwannomas: a review.
Welling DB, Packer MD, Chang LS. Welling DB, et al. Among authors: chang ls. Curr Opin Otolaryngol Head Neck Surg. 2007 Oct;15(5):341-6. doi: 10.1097/MOO.0b013e3282b97310. Curr Opin Otolaryngol Head Neck Surg. 2007. PMID: 17823551 Review.
Molecular biology of vestibular schwannomas.
Chang LS, Welling DB. Chang LS, et al. Methods Mol Biol. 2009;493:163-77. doi: 10.1007/978-1-59745-523-7_10. Methods Mol Biol. 2009. PMID: 18839347
AR42, a novel histone deacetylase inhibitor, as a potential therapy for vestibular schwannomas and meningiomas.
Bush ML, Oblinger J, Brendel V, Santarelli G, Huang J, Akhmametyeva EM, Burns SS, Wheeler J, Davis J, Yates CW, Chaudhury AR, Kulp S, Chen CS, Chang LS, Welling DB, Jacob A. Bush ML, et al. Among authors: chang ls. Neuro Oncol. 2011 Sep;13(9):983-99. doi: 10.1093/neuonc/nor072. Epub 2011 Jul 21. Neuro Oncol. 2011. PMID: 21778190 Free PMC article.
Treatment of vestibular schwannoma cells with ErbB inhibitors.
Bush ML, Burns SS, Oblinger J, Davletova S, Chang LS, Welling DB, Jacob A. Bush ML, et al. Among authors: chang ls. Otol Neurotol. 2012 Feb;33(2):244-57. doi: 10.1097/MAO.0b013e31823e287f. Otol Neurotol. 2012. PMID: 22222570 Free PMC article.
Histone deacetylase inhibitor AR-42 differentially affects cell-cycle transit in meningeal and meningioma cells, potently inhibiting NF2-deficient meningioma growth.
Burns SS, Akhmametyeva EM, Oblinger JL, Bush ML, Huang J, Senner V, Chen CS, Jacob A, Welling DB, Chang LS. Burns SS, et al. Among authors: chang ls. Cancer Res. 2013 Jan 15;73(2):792-803. doi: 10.1158/0008-5472.CAN-12-1888. Epub 2012 Nov 14. Cancer Res. 2013. PMID: 23151902 Free PMC article.
Ponatinib promotes a G1 cell-cycle arrest of merlin/NF2-deficient human schwann cells.
Petrilli AM, Garcia J, Bott M, Klingeman Plati S, Dinh CT, Bracho OR, Yan D, Zou B, Mittal R, Telischi FF, Liu XZ, Chang LS, Welling DB, Copik AJ, Fernández-Valle C. Petrilli AM, et al. Among authors: chang ls. Oncotarget. 2017 May 9;8(19):31666-31681. doi: 10.18632/oncotarget.15912. Oncotarget. 2017. PMID: 28427224 Free PMC article.
739 results