Baba M - Search Results

1

Synthesis, Anti-HBV, and Anti-HIV Activities of 3'-Halogenated Bis(hydroxymethyl)-cyclopentenyladenines.

Kumamoto H, Imoto S, Amano M, Kuwata-Higashi N, Baba M, Mitsuya H, Odanaka Y, Shimbara Matsubayashi S, Tanaka H, Haraguchi K. Kumamoto H, et al. Among authors: baba m. ACS Med Chem Lett. 2018 Nov 9;9(12):1211-1216. doi: 10.1021/acsmedchemlett.8b00374. eCollection 2018 Dec 13. ACS Med Chem Lett. 2018. PMID: 30613328 Free PMC article.

2

Synthesis and anti-human immunodeficiency virus activity of 4'-branched (+/-)-4'-thiostavudines.

Kumamoto H, Nakai T, Haraguchi K, Nakamura KT, Tanaka H, Baba M, Cheng YC. Kumamoto H, et al. Among authors: baba m. J Med Chem. 2006 Dec 28;49(26):7861-7. doi: 10.1021/jm060980j. J Med Chem. 2006. PMID: 17181169

3

Synthesis and anti-HIV activity of 4'-substituted 4'-thiothymidines: a new entry based on nucleophilic substitution of the 4'-acetoxy group.

Haraguchi K, Shimada H, Tanaka H, Hamasaki T, Baba M, Gullen EA, Dutschman GE, Cheng YC. Haraguchi K, et al. Among authors: baba m. J Med Chem. 2008 Mar 27;51(6):1885-93. doi: 10.1021/jm070824s. Epub 2008 Feb 27. J Med Chem. 2008. PMID: 18311897

4

Synthesis and anti-HIV-1 evaluation of phosphonates which mimic the 5'-monophosphate of 4'-branched 2',3'-didehydro-2',3'-dideoxy nucleosides.

Kubota Y, Ishizaki N, Haraguchi K, Hamasaki T, Baba M, Tanaka H. Kubota Y, et al. Among authors: baba m. Bioorg Med Chem. 2010 Oct 15;18(20):7186-92. doi: 10.1016/j.bmc.2010.08.037. Epub 2010 Aug 21. Bioorg Med Chem. 2010. PMID: 20833550

5

Synthesis of 4'-Ethynyl-2'-deoxy-4'-thioribonucleosides and Discovery of a Highly Potent and Less Toxic NRTI.

Haraguchi K, Shimada H, Kimura K, Akutsu G, Tanaka H, Abe H, Hamasaki T, Baba M, Gullen EA, Dutschman GE, Cheng YC, Balzarini J. Haraguchi K, et al. Among authors: baba m. ACS Med Chem Lett. 2011 Sep 8;2(9):692-697. doi: 10.1021/ml2001054. ACS Med Chem Lett. 2011. PMID: 23795238 Free PMC article.

6

Synthesis of a highly active new anti-HIV agent 2',3'-didehydro-3'-deoxy-4'-ethynylthymidine.

Haraguchi K, Takeda S, Tanaka H, Nitanda T, Baba M, Dutschman GE, Cheng YC. Haraguchi K, et al. Among authors: baba m. Bioorg Med Chem Lett. 2003 Nov 3;13(21):3775-7. doi: 10.1016/j.bmcl.2003.07.009. Bioorg Med Chem Lett. 2003. PMID: 14552777

7

Synthesis and antiviral activities of 1'-carbon-substituted 4'-thiothymidines.

Haraguchi K, Takahashi H, Tanaka H, Hayakawa H, Ashida N, Nitanda T, Baba M. Haraguchi K, et al. Among authors: baba m. Bioorg Med Chem. 2004 Oct 15;12(20):5309-16. doi: 10.1016/j.bmc.2004.07.057. Bioorg Med Chem. 2004. PMID: 15388158

8

Anti-human immunodeficiency virus type 1 activity and resistance profile of 2',3'-didehydro-3'-deoxy-4'-ethynylthymidine in vitro.

Nitanda T, Wang X, Kumamoto H, Haraguchi K, Tanaka H, Cheng YC, Baba M. Nitanda T, et al. Among authors: baba m. Antimicrob Agents Chemother. 2005 Aug;49(8):3355-60. doi: 10.1128/AAC.49.8.3355-3360.2005. Antimicrob Agents Chemother. 2005. PMID: 16048947 Free PMC article.

9

4'-Ethynylstavudine (4'-Ed4T) has potent anti-HIV-1 activity with reduced toxicity and shows a unique activity profile against drug-resistant mutants.

Tanaka H, Haraguchi K, Kumamoto H, Baba M, Cheng YC. Tanaka H, et al. Among authors: baba m. Antivir Chem Chemother. 2005;16(4):217-21. doi: 10.1177/095632020501600402. Antivir Chem Chemother. 2005. PMID: 16130520 Free article.

10

Synthesis and antiviral evaluation of (+/-)-4'-ethynyl-5'-difluorocarbocyclic-d4T analogue.

Kumamoto H, Haraguchi K, Ida M, Tanaka H, Hamasaki T, Baba M. Kumamoto H, et al. Among authors: baba m. Nucleic Acids Symp Ser (Oxf). 2008;(52):609-10. doi: 10.1093/nass/nrn308. Nucleic Acids Symp Ser (Oxf). 2008. PMID: 18776527

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