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Inhibition of telomerase activity by splice-switching oligonucleotides targeting the mRNA of the telomerase catalytic subunit affects proliferation of human CD4+ T lymphocytes.
Zhdanov DD, Plyasova AA, Gladilina YA, Pokrovsky VS, Grishin DV, Grachev VA, Orlova VS, Pokrovskaya MV, Alexandrova SS, Lobaeva TA, Sokolov NN. Zhdanov DD, et al. Among authors: gladilina ya. Biochem Biophys Res Commun. 2019 Feb 12;509(3):790-796. doi: 10.1016/j.bbrc.2018.12.186. Epub 2019 Jan 4. Biochem Biophys Res Commun. 2019. PMID: 30612734
Inhibition of telomerase activity and induction of apoptosis by Rhodospirillum rubrum L-asparaginase in cancer Jurkat cell line and normal human CD4+ T lymphocytes.
Zhdanov DD, Pokrovsky VS, Pokrovskaya MV, Alexandrova SS, Eldarov MA, Grishin DV, Basharov MM, Gladilina YA, Podobed OV, Sokolov NN. Zhdanov DD, et al. Among authors: gladilina ya. Cancer Med. 2017 Nov;6(11):2697-2712. doi: 10.1002/cam4.1218. Epub 2017 Oct 5. Cancer Med. 2017. PMID: 28984046 Free PMC article.
Murine regulatory T cells induce death of effector T, B, and NK lymphocytes through a contact-independent mechanism involving telomerase suppression and telomere-associated senescence.
Zhdanov DD, Gladilina YA, Pokrovsky VS, Grishin DV, Grachev VA, Orlova VS, Pokrovskaya MV, Alexandrova SS, Sokolov NN. Zhdanov DD, et al. Among authors: gladilina ya. Cell Immunol. 2018 Sep;331:146-160. doi: 10.1016/j.cellimm.2018.06.008. Epub 2018 Jun 19. Cell Immunol. 2018. PMID: 29935763
Mechanisms of the Antiproliferative and Antitumor Activity of Novel Telomerase-Carbonic Anhydrase Dual-Hybrid Inhibitors.
Plyasova AA, Berrino E, Khan II, Veselovsky AV, Pokrovsky VS, Angeli A, Ferraroni M, Supuran CT, Pokrovskaya MV, Alexandrova SS, Gladilina YA, Sokolov NN, Hilal A, Carta F, Zhdanov DD. Plyasova AA, et al. Among authors: gladilina ya. J Med Chem. 2021 Aug 12;64(15):11432-11444. doi: 10.1021/acs.jmedchem.1c00756. Epub 2021 Jul 20. J Med Chem. 2021. PMID: 34283610
New Genetic Bomb Trigger: Design, Synthesis, Molecular Dynamics Simulation, and Biological Evaluation of Novel BIBR1532-Related Analogs Targeting Telomerase against Non-Small Cell Lung Cancer.
Tawfik HO, El-Hamaky AA, El-Bastawissy EA, Shcherbakov KA, Veselovsky AV, Gladilina YA, Zhdanov DD, El-Hamamsy MH. Tawfik HO, et al. Among authors: gladilina ya. Pharmaceuticals (Basel). 2022 Apr 14;15(4):481. doi: 10.3390/ph15040481. Pharmaceuticals (Basel). 2022. PMID: 35455478 Free PMC article.
25 results