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Stereochemistry of phase-1 metabolites of mephedrone determines their effectiveness as releasers at the serotonin transporter.
Mayer FP, Cintulova D, Pittrich DA, Wimmer L, Luethi D, Holy M, Jaentsch K, Tischberger S, Gmeiner G, Hoener MC, Liechti ME, Mihovilovic MD, Sitte HH. Mayer FP, et al. Among authors: mihovilovic md. Neuropharmacology. 2019 Apr;148:199-209. doi: 10.1016/j.neuropharm.2018.12.032. Epub 2019 Jan 2. Neuropharmacology. 2019. PMID: 30610839
Efficient modulation of γ-aminobutyric acid type A receptors by piperine derivatives.
Schöffmann A, Wimmer L, Goldmann D, Khom S, Hintersteiner J, Baburin I, Schwarz T, Hintersteininger M, Pakfeifer P, Oufir M, Hamburger M, Erker T, Ecker GF, Mihovilovic MD, Hering S. Schöffmann A, et al. Among authors: mihovilovic md. J Med Chem. 2014 Jul 10;57(13):5602-19. doi: 10.1021/jm5002277. Epub 2014 Jun 27. J Med Chem. 2014. PMID: 24905252 Free PMC article.
Piperine Congeners as Inhibitors of Vascular Smooth Muscle Cell Proliferation.
Mair CE, Liu R, Atanasov AG, Wimmer L, Nemetz-Fiedler D, Sider N, Heiss EH, Mihovilovic MD, Dirsch VM, Rollinger JM. Mair CE, et al. Among authors: mihovilovic md. Planta Med. 2015 Aug;81(12-13):1065-74. doi: 10.1055/s-0035-1546165. Epub 2015 Jul 1. Planta Med. 2015. PMID: 26132851
GABAA receptor activity modulating piperine analogs: In vitro metabolic stability, metabolite identification, CYP450 reaction phenotyping, and protein binding.
Zabela V, Hettich T, Schlotterbeck G, Wimmer L, Mihovilovic MD, Guillet F, Bouaita B, Shevchenko B, Hamburger M, Oufir M. Zabela V, et al. Among authors: mihovilovic md. J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Jan 1;1072:379-389. doi: 10.1016/j.jchromb.2017.11.036. Epub 2017 Dec 2. J Chromatogr B Analyt Technol Biomed Life Sci. 2018. PMID: 29227934
Cellular N-myristoyltransferases play a crucial picornavirus genus-specific role in viral assembly, virion maturation, and infectivity.
Corbic Ramljak I, Stanger J, Real-Hohn A, Dreier D, Wimmer L, Redlberger-Fritz M, Fischl W, Klingel K, Mihovilovic MD, Blaas D, Kowalski H. Corbic Ramljak I, et al. Among authors: mihovilovic md. PLoS Pathog. 2018 Aug 6;14(8):e1007203. doi: 10.1371/journal.ppat.1007203. eCollection 2018 Aug. PLoS Pathog. 2018. PMID: 30080883 Free PMC article.
127 results