Talapatra SK - Search Results

1

Development and validation of RdRp Screen, a crystallization screen for viral RNA-dependent RNA polymerases.

Riccio F, Talapatra SK, Oxenford S, Angell R, Mazzon M, Kozielski F. Riccio F, et al. Among authors: talapatra sk. Biol Open. 2019 Jan 2;8(1):bio037663. doi: 10.1242/bio.037663. Biol Open. 2019. PMID: 30602529 Free PMC article.

2

The structure of the binary methyltransferase-SAH complex from Zika virus reveals a novel conformation for the mechanism of mRNA capping.

Chatrin C, Talapatra SK, Canard B, Kozielski F. Chatrin C, et al. Among authors: talapatra sk. Oncotarget. 2017 Dec 14;9(3):3160-3171. doi: 10.18632/oncotarget.23223. eCollection 2018 Jan 9. Oncotarget. 2017. PMID: 29423037 Free PMC article.

3

Modified Peptide Inhibitors of the Keap1-Nrf2 Protein-Protein Interaction Incorporating Unnatural Amino Acids.

Georgakopoulos ND, Talapatra SK, Gatliff J, Kozielski F, Wells G. Georgakopoulos ND, et al. Among authors: talapatra sk. Chembiochem. 2018 Sep 4;19(17):1810-1816. doi: 10.1002/cbic.201800170. Epub 2018 Jul 18. Chembiochem. 2018. PMID: 29927029 Free PMC article.

4

New MKLP-2 inhibitors in the paprotrain series: Design, synthesis and biological evaluations.

Labrière C, Talapatra SK, Thoret S, Bougeret C, Kozielski F, Guillou C. Labrière C, et al. Among authors: talapatra sk. Bioorg Med Chem. 2016 Feb 15;24(4):721-34. doi: 10.1016/j.bmc.2015.12.042. Epub 2015 Dec 24. Bioorg Med Chem. 2016. PMID: 26778612

5

The structure of the ternary Eg5-ADP-ispinesib complex.

Talapatra SK, Schüttelkopf AW, Kozielski F. Talapatra SK, et al. Acta Crystallogr D Biol Crystallogr. 2012 Oct;68(Pt 10):1311-9. doi: 10.1107/S0907444912027965. Epub 2012 Sep 13. Acta Crystallogr D Biol Crystallogr. 2012. PMID: 22993085 Free PMC article.

6

Crystal structure of the Eg5 - K858 complex and implications for structure-based design of thiadiazole-containing inhibitors.

Talapatra SK, Tham CL, Guglielmi P, Cirilli R, Chandrasekaran B, Karpoormath R, Carradori S, Kozielski F. Talapatra SK, et al. Eur J Med Chem. 2018 Aug 5;156:641-651. doi: 10.1016/j.ejmech.2018.07.006. Epub 2018 Jul 4. Eur J Med Chem. 2018. PMID: 30031975

7

Is the Fate of Clinical Candidate Arry-520 Already Sealed? Predicting Resistance in Eg5-Inhibitor Complexes.

Indorato RL, Talapatra SK, Lin F, Haider S, Mackay SP, Kozielski F, Skoufias DA. Indorato RL, et al. Among authors: talapatra sk. Mol Cancer Ther. 2019 Dec;18(12):2394-2406. doi: 10.1158/1535-7163.MCT-19-0154. Epub 2019 Sep 5. Mol Cancer Ther. 2019. PMID: 31488701 Free article.

8

Depsidones from Lichens as Natural Product Inhibitors of M-Phase Phosphoprotein 1, a Human Kinesin Required for Cytokinesis.

Talapatra SK, Rath O, Clayton E, Tomasi S, Kozielski F. Talapatra SK, et al. J Nat Prod. 2016 Jun 24;79(6):1576-85. doi: 10.1021/acs.jnatprod.5b00962. Epub 2016 Jun 14. J Nat Prod. 2016. PMID: 27300079

9

Mitotic kinesin Eg5 overcomes inhibition to the phase I/II clinical candidate SB743921 by an allosteric resistance mechanism.

Talapatra SK, Anthony NG, Mackay SP, Kozielski F. Talapatra SK, et al. J Med Chem. 2013 Aug 22;56(16):6317-29. doi: 10.1021/jm4006274. J Med Chem. 2013. PMID: 23875972 Clinical Trial.

10

Structural insights into a unique inhibitor binding pocket in kinesin spindle protein.

Ulaganathan V, Talapatra SK, Rath O, Pannifer A, Hackney DD, Kozielski F. Ulaganathan V, et al. Among authors: talapatra sk. J Am Chem Soc. 2013 Feb 13;135(6):2263-72. doi: 10.1021/ja310377d. Epub 2013 Feb 4. J Am Chem Soc. 2013. PMID: 23305346

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