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Page 1
Gene Transfer with AAV9-PHP.B Rescues Hearing in a Mouse Model of Usher Syndrome 3A and Transduces Hair Cells in a Non-human Primate.
György B, Meijer EJ, Ivanchenko MV, Tenneson K, Emond F, Hanlon KS, Indzhykulian AA, Volak A, Karavitaki KD, Tamvakologos PI, Vezina M, Berezovskii VK, Born RT, O'Brien M, Lafond JF, Arsenijevic Y, Kenna MA, Maguire CA, Corey DP. György B, et al. Among authors: hanlon ks. Mol Ther Methods Clin Dev. 2018 Nov 20;13:1-13. doi: 10.1016/j.omtm.2018.11.003. eCollection 2019 Jun 14. Mol Ther Methods Clin Dev. 2018. PMID: 30581889 Free PMC article.
High levels of AAV vector integration into CRISPR-induced DNA breaks.
Hanlon KS, Kleinstiver BP, Garcia SP, Zaborowski MP, Volak A, Spirig SE, Muller A, Sousa AA, Tsai SQ, Bengtsson NE, Lööv C, Ingelsson M, Chamberlain JS, Corey DP, Aryee MJ, Joung JK, Breakefield XO, Maguire CA, György B. Hanlon KS, et al. Nat Commun. 2019 Sep 30;10(1):4439. doi: 10.1038/s41467-019-12449-2. Nat Commun. 2019. PMID: 31570731 Free PMC article.
Selection of an Efficient AAV Vector for Robust CNS Transgene Expression.
Hanlon KS, Meltzer JC, Buzhdygan T, Cheng MJ, Sena-Esteves M, Bennett RE, Sullivan TP, Razmpour R, Gong Y, Ng C, Nammour J, Maiz D, Dujardin S, Ramirez SH, Hudry E, Maguire CA. Hanlon KS, et al. Mol Ther Methods Clin Dev. 2019 Oct 23;15:320-332. doi: 10.1016/j.omtm.2019.10.007. eCollection 2019 Dec 13. Mol Ther Methods Clin Dev. 2019. PMID: 31788496 Free PMC article.
Delivering AAV to the Central Nervous and Sensory Systems.
Peters CW, Maguire CA, Hanlon KS. Peters CW, et al. Among authors: hanlon ks. Trends Pharmacol Sci. 2021 Jun;42(6):461-474. doi: 10.1016/j.tips.2021.03.004. Epub 2021 Apr 13. Trends Pharmacol Sci. 2021. PMID: 33863599 Free PMC article. Review.
AAV-S: A versatile capsid variant for transduction of mouse and primate inner ear.
Ivanchenko MV, Hanlon KS, Hathaway DM, Klein AJ, Peters CW, Li Y, Tamvakologos PI, Nammour J, Maguire CA, Corey DP. Ivanchenko MV, et al. Among authors: hanlon ks. Mol Ther Methods Clin Dev. 2021 Mar 29;21:382-398. doi: 10.1016/j.omtm.2021.03.019. eCollection 2021 Jun 11. Mol Ther Methods Clin Dev. 2021. PMID: 33869656 Free PMC article.
The AAV9 Variant Capsid AAV-F Mediates Widespread Transgene Expression in Nonhuman Primate Spinal Cord After Intrathecal Administration.
Beharry A, Gong Y, Kim JC, Hanlon KS, Nammour J, Hieber K, Eichler F, Cheng M, Stemmer-Rachamimov A, Stankovic KM, Welling DB, Ng C, Maguire CA. Beharry A, et al. Among authors: hanlon ks. Hum Gene Ther. 2022 Jan;33(1-2):61-75. doi: 10.1089/hum.2021.069. Epub 2021 Aug 26. Hum Gene Ther. 2022. PMID: 34128391 Free PMC article.
An Engineered Adeno-Associated Virus Capsid Mediates Efficient Transduction of Pericytes and Smooth Muscle Cells of the Brain Vasculature.
Ramirez SH, Hale JF, McCarthy S, Cardenas CL, Dona KNUG, Hanlon KS, Hudry E, Cruz D, Ng C, Das S, Nguyen DM, Nammour J, Bennett RE, Andrews AM, Musolino PL, Maguire CA. Ramirez SH, et al. Among authors: hanlon ks. Hum Gene Ther. 2023 Aug;34(15-16):682-696. doi: 10.1089/hum.2022.211. Hum Gene Ther. 2023. PMID: 37376759 Free PMC article.
18 results