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Delta spike P681R mutation enhances SARS-CoV-2 fitness over Alpha variant.
Liu Y, Liu J, Johnson BA, Xia H, Ku Z, Schindewolf C, Widen SG, An Z, Weaver SC, Menachery VD, Xie X, Shi PY. Liu Y, et al. Among authors: menachery vd. bioRxiv [Preprint]. 2021 Sep 5:2021.08.12.456173. doi: 10.1101/2021.08.12.456173. bioRxiv. 2021. Update in: Cell Rep. 2022 May 17;39(7):110829. doi: 10.1016/j.celrep.2022.110829 PMID: 34462752 Free PMC article. Updated. Preprint.
TRIM7 ubiquitinates SARS-CoV-2 membrane protein to limit apoptosis and viral replication.
Gonzalez-Orozco M, Tseng HC, Hage A, Xia H, Behera P, Afreen K, Peñaflor-Tellez Y, Giraldo MI, Huante M, Puebla-Clark L, van Tol S, Odle A, Crown M, Teruel N, Shelite TR, Menachery V, Endsley M, Endsley JJ, Najmanovich RJ, Bashton M, Stephens R, Shi PY, Xie X, Freiberg AN, Rajsbaum R. Gonzalez-Orozco M, et al. bioRxiv [Preprint]. 2024 Jun 17:2024.06.17.599107. doi: 10.1101/2024.06.17.599107. bioRxiv. 2024. Update in: Nat Commun. 2024 Nov 30;15(1):10438. doi: 10.1038/s41467-024-54762-5 PMID: 38948778 Free PMC article. Updated. Preprint.
Tiled-ClickSeq for targeted sequencing of complete coronavirus genomes with simultaneous capture of RNA recombination and minority variants.
Jaworski E, Langsjoen RM, Mitchell B, Judy B, Newman P, Plante JA, Plante KS, Miller AL, Zhou Y, Swetnam D, Sotcheff S, Morris V, Saada N, Machado R, McConnell A, Widen S, Thompson J, Dong J, Ren P, Pyles RB, Ksiazek T, Menachery VD, Weaver SC, Routh A. Jaworski E, et al. Among authors: menachery vd. bioRxiv [Preprint]. 2021 Sep 1:2021.03.10.434828. doi: 10.1101/2021.03.10.434828. bioRxiv. 2021. Update in: Elife. 2021 Sep 28;10:e68479. doi: 10.7554/eLife.68479 PMID: 33758846 Free PMC article. Updated. Preprint.
Engineering SARS-CoV-2 cocktail antibodies into a bispecific format improves neutralizing potency and breadth.
Ku Z, Xie X, Lin J, Gao P, El Sahili A, Su H, Liu Y, Ye X, Li X, Fan X, Goh BC, Xiong W, Boyd H, Muruato AE, Deng H, Xia H, Jing Z, Kalveram BK, Menachery VD, Zhang N, Lescar J, Shi PY, An Z. Ku Z, et al. Among authors: menachery vd. bioRxiv [Preprint]. 2022 Feb 1:2022.02.01.478504. doi: 10.1101/2022.02.01.478504. bioRxiv. 2022. Update in: Nat Commun. 2022 Sep 22;13(1):5552. doi: 10.1038/s41467-022-33284-y PMID: 35132410 Free PMC article. Updated. Preprint.
SARS-CoV-2 hijacks fragile X mental retardation proteins for efficient infection.
Garvanska DH, Alvarado RE, Mundt FO, Nilsson E, Duel JK, Coscia F, Lindqvist R, Lokugamage K, Johnson BA, Plante JA, Morris DR, Vu MN, Estes LK, McLeland AM, Walker J, Crocquet-Valdes PA, Mendez BL, Plante KS, Walker DH, Weisser MB, Overby AK, Mann M, Menachery VD, Nilsson J. Garvanska DH, et al. Among authors: menachery vd. bioRxiv [Preprint]. 2023 Sep 1:2023.09.01.555899. doi: 10.1101/2023.09.01.555899. bioRxiv. 2023. PMID: 37693415 Free PMC article. Preprint.
Loss-of-function mutation in Omicron variants reduces spike protein expression and attenuates SARS-CoV-2 infection.
Vu MN, Alvarado RE, Morris DR, Lokugamage KG, Zhou Y, Morgan AL, Estes LK, McLeland AM, Schindewolf C, Plante JA, Ahearn YP, Meyers WM, Murray JT, Crocquet-Valdes PA, Weaver SC, Walker DH, Russell WK, Routh AL, Plante KS, Menachery V. Vu MN, et al. bioRxiv [Preprint]. 2023 Jul 10:2023.04.17.536926. doi: 10.1101/2023.04.17.536926. bioRxiv. 2023. PMID: 37131784 Free PMC article. Preprint.
A live-attenuated SARS-CoV-2 vaccine candidate with accessory protein deletions.
Liu Y, Zhang X, Liu J, Xia H, Zou J, Muruato AE, Periasamy S, Plante JA, Bopp NE, Kurhade C, Bukreyev A, Ren P, Wang T, Menachery VD, Plante KS, Xie X, Weaver SC, Shi PY. Liu Y, et al. Among authors: menachery vd. bioRxiv [Preprint]. 2022 Feb 15:2022.02.14.480460. doi: 10.1101/2022.02.14.480460. bioRxiv. 2022. Update in: Nat Commun. 2022 Jul 27;13(1):4337. doi: 10.1038/s41467-022-31930-z PMID: 35194609 Free PMC article. Updated. Preprint.
The NSP3 protein of SARS-CoV-2 binds fragile X mental retardation proteins to disrupt UBAP2L interactions.
Garvanska DH, Alvarado RE, Mundt FO, Lindqvist R, Duel JK, Coscia F, Nilsson E, Lokugamage K, Johnson BA, Plante JA, Morris DR, Vu MN, Estes LK, McLeland AM, Walker J, Crocquet-Valdes PA, Mendez BL, Plante KS, Walker DH, Weisser MB, Överby AK, Mann M, Menachery VD, Nilsson J. Garvanska DH, et al. Among authors: menachery vd. EMBO Rep. 2024 Feb;25(2):902-926. doi: 10.1038/s44319-023-00043-z. Epub 2024 Jan 2. EMBO Rep. 2024. PMID: 38177924 Free PMC article.
Release of severe acute respiratory syndrome coronavirus nuclear import block enhances host transcription in human lung cells.
Sims AC, Tilton SC, Menachery VD, Gralinski LE, Schäfer A, Matzke MM, Webb-Robertson BJ, Chang J, Luna ML, Long CE, Shukla AK, Bankhead AR 3rd, Burkett SE, Zornetzer G, Tseng CT, Metz TO, Pickles R, McWeeney S, Smith RD, Katze MG, Waters KM, Baric RS. Sims AC, et al. Among authors: menachery vd. J Virol. 2013 Apr;87(7):3885-902. doi: 10.1128/JVI.02520-12. Epub 2013 Jan 30. J Virol. 2013. PMID: 23365422 Free PMC article.
149 results