So HC - Search Results

1

Translating GWAS findings into therapies for depression and anxiety disorders: gene-set analyses reveal enrichment of psychiatric drug classes and implications for drug repositioning.

So HC, Chau CK, Lau A, Wong SY, Zhao K. So HC, et al. Psychol Med. 2019 Dec;49(16):2692-2708. doi: 10.1017/S0033291718003641. Epub 2018 Dec 20. Psychol Med. 2019. PMID: 30569882

2

Exploring the predictive power of polygenic scores derived from genome-wide association studies: a study of 10 complex traits.

So HC, Sham PC. So HC, et al. Bioinformatics. 2017 Mar 15;33(6):886-892. doi: 10.1093/bioinformatics/btw745. Bioinformatics. 2017. PMID: 28065900

3

Analysis of genome-wide association data highlights candidates for drug repositioning in psychiatry.

So HC, Chau CK, Chiu WT, Ho KS, Lo CP, Yim SH, Sham PC. So HC, et al. Nat Neurosci. 2017 Oct;20(10):1342-1349. doi: 10.1038/nn.4618. Epub 2017 Aug 14. Nat Neurosci. 2017. PMID: 28805813

4

Analysis of shared heritability in common disorders of the brain.

Brainstorm Consortium; Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, Duncan L, Escott-Price V, Falcone GJ, Gormley P, Malik R, Patsopoulos NA, Ripke S, Wei Z, Yu D, Lee PH, Turley P, Grenier-Boley B, Chouraki V, Kamatani Y, Berr C, Letenneur L, Hannequin D, Amouyel P, Boland A, Deleuze JF, Duron E, Vardarajan BN, Reitz C, Goate AM, Huentelman MJ, Kamboh MI, Larson EB, Rogaeva E, St George-Hyslop P, Hakonarson H, Kukull WA, Farrer LA, Barnes LL, Beach TG, Demirci FY, Head E, Hulette CM, Jicha GA, Kauwe JSK, Kaye JA, Leverenz JB, Levey AI, Lieberman AP, Pankratz VS, Poon WW, Quinn JF, Saykin AJ, Schneider LS, Smith AG, Sonnen JA, Stern RA, Van Deerlin VM, Van Eldik LJ, Harold D, Russo G, Rubinsztein DC, Bayer A, Tsolaki M, Proitsi P, Fox NC, Hampel H, Owen MJ, Mead S, Passmore P, Morgan K, Nöthen MM, Rossor M, Lupton MK, Hoffmann P, Kornhuber J, Lawlor B, McQuillin A, Al-Chalabi A, Bis JC, Ruiz A, Boada M, Seshadri S, Beiser A, Rice K, van der Lee SJ, De Jager PL, Geschwind DH, Riemenschneider M, Riedel-Heller S, Rotter JI, Ransmayr G, Hyman BT, Cruchaga C, Alegret M, Winsvold B, Palta P, Farh KH, Cuenca-Leon E, Furlotte N, Kurth T, Ligthart L, Terwindt GM, Freilinge… See abstract for full author list ➔ Brainstorm Consortium, et al. Among authors: so hc. Science. 2018 Jun 22;360(6395):eaap8757. doi: 10.1126/science.aap8757. Science. 2018. PMID: 29930110 Free PMC article.

5

Drug Repositioning for Schizophrenia and Depression/Anxiety Disorders: A Machine Learning Approach Leveraging Expression Data.

Zhao K, So HC. Zhao K, et al. Among authors: so hc. IEEE J Biomed Health Inform. 2019 May;23(3):1304-1315. doi: 10.1109/JBHI.2018.2856535. Epub 2018 Jul 16. IEEE J Biomed Health Inform. 2019. PMID: 30010603

6

Exploring shared genetic bases and causal relationships of schizophrenia and bipolar disorder with 28 cardiovascular and metabolic traits.

So HC, Chau KL, Ao FK, Mo CH, Sham PC. So HC, et al. Psychol Med. 2019 Jun;49(8):1286-1298. doi: 10.1017/S0033291718001812. Epub 2018 Jul 26. Psychol Med. 2019. PMID: 30045777

7

Leveraging genome-wide association and clinical data in revealing schizophrenia subgroups.

Yin L, Cheung EF, Chen RY, Wong EH, Sham PC, So HC. Yin L, et al. Among authors: so hc. J Psychiatr Res. 2018 Nov;106:106-117. doi: 10.1016/j.jpsychires.2018.09.010. Epub 2018 Sep 22. J Psychiatr Res. 2018. PMID: 30312963

8

Differential associations of depression-related phenotypes with cardiometabolic risks: Polygenic analyses and exploring shared genetic variants and pathways.

Wong BC, Chau CK, Ao FK, Mo CH, Wong SY, Wong YH, So HC. Wong BC, et al. Among authors: so hc. Depress Anxiety. 2019 Apr;36(4):330-344. doi: 10.1002/da.22861. Epub 2018 Dec 6. Depress Anxiety. 2019. PMID: 30521077

9

Using Drug Expression Profiles and Machine Learning Approach for Drug Repurposing.

Zhao K, So HC. Zhao K, et al. Among authors: so hc. Methods Mol Biol. 2019;1903:219-237. doi: 10.1007/978-1-4939-8955-3_13. Methods Mol Biol. 2019. PMID: 30547445 Review.

10

Implications of de novo mutations in guiding drug discovery: A study of four neuropsychiatric disorders.

So HC, Wong YH. So HC, et al. J Psychiatr Res. 2019 Mar;110:83-92. doi: 10.1016/j.jpsychires.2018.12.015. Epub 2018 Dec 14. J Psychiatr Res. 2019. PMID: 30597425

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