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Complement C3a and C5a receptors promote GVHD by suppressing mitophagy in recipient dendritic cells.
Nguyen H, Kuril S, Bastian D, Kim J, Zhang M, Vaena SG, Dany M, Dai M, Heinrichs JL, Daenthanasanmak A, Iamsawat S, Schutt S, Fu J, Wu Y, Fairlie DP, Atkinson C, Ogretmen B, Tomlinson S, Yu XZ. Nguyen H, et al. Among authors: ogretmen b. JCI Insight. 2018 Dec 20;3(24):e121697. doi: 10.1172/jci.insight.121697. JCI Insight. 2018. PMID: 30568037 Free PMC article.
Ceramide synthase 6 (CerS6) is upregulated in alcohol-associated liver disease and exhibits sex-based differences in the regulation of energy homeostasis and lipid droplet accumulation.
Jeon S, Scorletti E, Dempsey J, Buyco D, Lin C, Saiman Y, Bayen S, Harkin J, Martin J, Hooks R, Ogretmen B, Argemi J, Melo L, Bataller R, Carr RM. Jeon S, et al. Among authors: ogretmen b. Mol Metab. 2023 Dec;78:101804. doi: 10.1016/j.molmet.2023.101804. Epub 2023 Sep 14. Mol Metab. 2023. PMID: 37714377 Free PMC article.
Ceramide induced mitophagy and tumor suppression.
Dany M, Ogretmen B. Dany M, et al. Among authors: ogretmen b. Biochim Biophys Acta. 2015 Oct;1853(10 Pt B):2834-45. doi: 10.1016/j.bbamcr.2014.12.039. Epub 2015 Jan 26. Biochim Biophys Acta. 2015. PMID: 25634657 Free PMC article. Review.
Ceramide synthesis regulates T cell activity and GVHD development.
Sofi MH, Heinrichs J, Dany M, Nguyen H, Dai M, Bastian D, Schutt S, Wu Y, Daenthanasanmak A, Gencer S, Zivkovic A, Szulc Z, Stark H, Liu C, Chang YJ, Ogretmen B, Yu XZ. Sofi MH, et al. Among authors: ogretmen b. JCI Insight. 2017 May 18;2(10):e91701. doi: 10.1172/jci.insight.91701. eCollection 2017 May 18. JCI Insight. 2017. PMID: 28515365 Free PMC article.
CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response.
Chatterjee S, Daenthanasanmak A, Chakraborty P, Wyatt MW, Dhar P, Selvam SP, Fu J, Zhang J, Nguyen H, Kang I, Toth K, Al-Homrani M, Husain M, Beeson G, Ball L, Helke K, Husain S, Garrett-Mayer E, Hardiman G, Mehrotra M, Nishimura MI, Beeson CC, Bupp MG, Wu J, Ogretmen B, Paulos CM, Rathmell J, Yu XZ, Mehrotra S. Chatterjee S, et al. Among authors: ogretmen b. Cell Metab. 2018 Jan 9;27(1):85-100.e8. doi: 10.1016/j.cmet.2017.10.006. Epub 2017 Nov 9. Cell Metab. 2018. PMID: 29129787 Free PMC article.
Receptor-interacting Ser/Thr kinase 1 (RIPK1) and myosin IIA-dependent ceramidosomes form membrane pores that mediate blebbing and necroptosis.
Nganga R, Oleinik N, Kim J, Selvam SP, De Palma R, Johnson KA, Parikh RY, Gangaraju V, Peterson Y, Dany M, Stahelin RV, Voelkel-Johnson C, Szulc ZM, Bieberich E, Ogretmen B. Nganga R, et al. Among authors: ogretmen b. J Biol Chem. 2019 Jan 11;294(2):502-519. doi: 10.1074/jbc.RA118.005865. Epub 2018 Nov 12. J Biol Chem. 2019. PMID: 30420430 Free PMC article.
146 results