Ito N - Search Results

1

Dual conformation of the ligand induces the partial agonistic activity of retinoid X receptor α (RXRα).

Miyashita Y, Numoto N, Arulmozhiraja S, Nakano S, Matsuo N, Shimizu K, Shibahara O, Fujihara M, Kakuta H, Ito S, Ikura T, Ito N, Tokiwa H. Miyashita Y, et al. Among authors: ito s, ito n. FEBS Lett. 2019 Jan;593(2):242-250. doi: 10.1002/1873-3468.13301. Epub 2018 Dec 21. FEBS Lett. 2019. PMID: 30565665 Free article.

2

Requirements for peptidyl-prolyl isomerization activity: a comprehensive mutational analysis of the substrate-binding cavity of FK506-binding protein 12.

Ikura T, Ito N. Ikura T, et al. Among authors: ito n. Protein Sci. 2007 Dec;16(12):2618-25. doi: 10.1110/ps.073203707. Protein Sci. 2007. PMID: 18029417 Free PMC article.

3

A cavity with an appropriate size is the basis of the PPIase activity.

Ikura T, Kinoshita K, Ito N. Ikura T, et al. Among authors: ito n. Protein Eng Des Sel. 2008 Feb;21(2):83-9. doi: 10.1093/protein/gzm087. Epub 2008 Jan 5. Protein Eng Des Sel. 2008. PMID: 18175776

4

Crystal structural analysis of protein-protein interactions drastically destabilized by a single mutation.

Urakubo Y, Ikura T, Ito N. Urakubo Y, et al. Among authors: ito n. Protein Sci. 2008 Jun;17(6):1055-65. doi: 10.1110/ps.073322508. Epub 2008 Apr 25. Protein Sci. 2008. PMID: 18441234 Free PMC article.

5

2-Substituted-16-ene-22-thia-1alpha,25-dihydroxy-26,27-dimethyl-19-norvitamin D3 analogs: Synthesis, biological evaluation, and crystal structure.

Shimizu M, Miyamoto Y, Takaku H, Matsuo M, Nakabayashi M, Masuno H, Udagawa N, DeLuca HF, Ikura T, Ito N. Shimizu M, et al. Among authors: ito n. Bioorg Med Chem. 2008 Jul 15;16(14):6949-64. doi: 10.1016/j.bmc.2008.05.043. Epub 2008 May 27. Bioorg Med Chem. 2008. PMID: 18539034

6

Crystal structures of rat vitamin D receptor bound to adamantyl vitamin D analogs: structural basis for vitamin D receptor antagonism and partial agonism.

Nakabayashi M, Yamada S, Yoshimoto N, Tanaka T, Igarashi M, Ikura T, Ito N, Makishima M, Tokiwa H, DeLuca HF, Shimizu M. Nakabayashi M, et al. Among authors: ito n. J Med Chem. 2008 Sep 11;51(17):5320-9. doi: 10.1021/jm8004477. Epub 2008 Aug 19. J Med Chem. 2008. PMID: 18710208

7

A new class of vitamin D analogues that induce structural rearrangement of the ligand-binding pocket of the receptor.

Inaba Y, Yoshimoto N, Sakamaki Y, Nakabayashi M, Ikura T, Tamamura H, Ito N, Shimizu M, Yamamoto K. Inaba Y, et al. Among authors: ito n. J Med Chem. 2009 Mar 12;52(5):1438-49. doi: 10.1021/jm8014348. J Med Chem. 2009. PMID: 19193059

8

[Correlation between structure and function of peptidyl-prolyl isomerase].

Ikura T, Kinoshita K, Ito N. Ikura T, et al. Among authors: ito n. Tanpakushitsu Kakusan Koso. 2009 Feb;54(2):167-72. Tanpakushitsu Kakusan Koso. 2009. PMID: 19205352 Review. Japanese. No abstract available.

9

22S-butyl-1alpha,24R-dihydroxyvitamin D3: recovery of vitamin D receptor agonistic activity.

Inaba Y, Nakabayashi M, Itoh T, Yoshimoto N, Ikura T, Ito N, Shimizu M, Yamamoto K. Inaba Y, et al. Among authors: ito n. J Steroid Biochem Mol Biol. 2010 Jul;121(1-2):146-50. doi: 10.1016/j.jsbmb.2010.02.033. Epub 2010 Mar 6. J Steroid Biochem Mol Biol. 2010. PMID: 20211257

10

Development of a novel selective inhibitor of the Down syndrome-related kinase Dyrk1A.

Ogawa Y, Nonaka Y, Goto T, Ohnishi E, Hiramatsu T, Kii I, Yoshida M, Ikura T, Onogi H, Shibuya H, Hosoya T, Ito N, Hagiwara M. Ogawa Y, et al. Among authors: ito n. Nat Commun. 2010 Oct 5;1:86. doi: 10.1038/ncomms1090. Nat Commun. 2010. PMID: 20981014 Free article.

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