Alzayady KJ - Search Results

1

All three IP₃ receptor isoforms generate Ca²⁺ puffs that display similar characteristics.

Lock JT, Alzayady KJ, Yule DI, Parker I. Lock JT, et al. Among authors: alzayady kj. Sci Signal. 2018 Dec 18;11(561):eaau0344. doi: 10.1126/scisignal.aau0344. Sci Signal. 2018. PMID: 30563861 Free PMC article.

2

Fragmented inositol 1,4,5-trisphosphate receptors retain tetrameric architecture and form functional Ca2+ release channels.

Alzayady KJ, Chandrasekhar R, Yule DI. Alzayady KJ, et al. J Biol Chem. 2013 Apr 19;288(16):11122-34. doi: 10.1074/jbc.M113.453241. Epub 2013 Mar 11. J Biol Chem. 2013. PMID: 23479737 Free PMC article.

3

Using concatenated subunits to investigate the functional consequences of heterotetrameric inositol 1,4,5-trisphosphate receptors.

Chandrasekhar R, Alzayady KJ, Yule DI. Chandrasekhar R, et al. Among authors: alzayady kj. Biochem Soc Trans. 2015 Jun;43(3):364-70. doi: 10.1042/BST20140287. Biochem Soc Trans. 2015. PMID: 26009177 Free PMC article. Review.

4

Proteolytic fragmentation of inositol 1,4,5-trisphosphate receptors: a novel mechanism regulating channel activity?

Wang L, Alzayady KJ, Yule DI. Wang L, et al. Among authors: alzayady kj. J Physiol. 2016 Jun 1;594(11):2867-76. doi: 10.1113/JP271140. Epub 2015 Dec 7. J Physiol. 2016. PMID: 26486785 Free PMC article. Review.

5

Unique Regulatory Properties of Heterotetrameric Inositol 1,4,5-Trisphosphate Receptors Revealed by Studying Concatenated Receptor Constructs.

Chandrasekhar R, Alzayady KJ, Wagner LE 2nd, Yule DI. Chandrasekhar R, et al. Among authors: alzayady kj. J Biol Chem. 2016 Mar 4;291(10):4846-60. doi: 10.1074/jbc.M115.705301. Epub 2016 Jan 11. J Biol Chem. 2016. PMID: 26755721 Free PMC article.

6

Defining the stoichiometry of inositol 1,4,5-trisphosphate binding required to initiate Ca2+ release.

Alzayady KJ, Wang L, Chandrasekhar R, Wagner LE 2nd, Van Petegem F, Yule DI. Alzayady KJ, et al. Sci Signal. 2016 Apr 5;9(422):ra35. doi: 10.1126/scisignal.aad6281. Sci Signal. 2016. PMID: 27048566 Free PMC article.

7

Region-specific proteolysis differentially modulates type 2 and type 3 inositol 1,4,5-trisphosphate receptor activity in models of acute pancreatitis.

Wang L, Wagner LE 2nd, Alzayady KJ, Yule DI. Wang L, et al. Among authors: alzayady kj. J Biol Chem. 2018 Aug 24;293(34):13112-13124. doi: 10.1074/jbc.RA118.003421. Epub 2018 Jul 3. J Biol Chem. 2018. PMID: 29970616 Free PMC article.

8

Disease-associated mutations in inositol 1,4,5-trisphosphate receptor subunits impair channel function.

Terry LE, Alzayady KJ, Wahl AM, Malik S, Yule DI. Terry LE, et al. Among authors: alzayady kj. J Biol Chem. 2020 Dec 25;295(52):18160-18178. doi: 10.1074/jbc.RA120.015683. Epub 2020 Oct 22. J Biol Chem. 2020. PMID: 33093175 Free PMC article.

9

Functional inositol 1,4,5-trisphosphate receptors assembled from concatenated homo- and heteromeric subunits.

Alzayady KJ, Wagner LE 2nd, Chandrasekhar R, Monteagudo A, Godiska R, Tall GG, Joseph SK, Yule DI. Alzayady KJ, et al. J Biol Chem. 2013 Oct 11;288(41):29772-84. doi: 10.1074/jbc.M113.502203. Epub 2013 Aug 16. J Biol Chem. 2013. PMID: 23955339 Free PMC article.

10

Tracing the Evolutionary History of Inositol, 1, 4, 5-Trisphosphate Receptor: Insights from Analyses of Capsaspora owczarzaki Ca2+ Release Channel Orthologs.

Alzayady KJ, Sebé-Pedrós A, Chandrasekhar R, Wang L, Ruiz-Trillo I, Yule DI. Alzayady KJ, et al. Mol Biol Evol. 2015 Sep;32(9):2236-53. doi: 10.1093/molbev/msv098. Epub 2015 Apr 23. Mol Biol Evol. 2015. PMID: 25911230 Free PMC article.

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