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203 results

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A Phase 1 dose escalating study of double mutant heat-labile toxin LTR192G/L211A (dmLT) from Enterotoxigenic Escherichia coli (ETEC) by sublingual or oral immunization.
Bernstein DI, Pasetti MF, Brady R, Buskirk AD, Wahid R, Dickey M, Cohen M, Baughman H, El-Khorazaty J, Maier N, Sztein MB, Baqar S, Bourgeois AL. Bernstein DI, et al. Among authors: maier n. Vaccine. 2019 Jan 21;37(4):602-611. doi: 10.1016/j.vaccine.2018.12.011. Epub 2018 Dec 15. Vaccine. 2019. PMID: 30563789 Free PMC article. Clinical Trial.
Developing and utilizing controlled human models of infection.
Porter CK, Louis Bourgeois A, Frenck RW, Prouty M, Maier N, Riddle MS. Porter CK, et al. Among authors: maier n. Vaccine. 2017 Dec 14;35(49 Pt A):6813-6818. doi: 10.1016/j.vaccine.2017.05.068. Epub 2017 Jun 3. Vaccine. 2017. PMID: 28583306 Free article.
Impact of lower challenge doses of enterotoxigenic Escherichia coli on clinical outcome, intestinal colonization and immune responses in adult volunteers.
Chakraborty S, Harro C, DeNearing B, Brubaker J, Connor S, Maier N, Dally L, Flores J, Bourgeois AL, Walker R, Sack DA. Chakraborty S, et al. Among authors: maier n. PLoS Negl Trop Dis. 2018 Apr 27;12(4):e0006442. doi: 10.1371/journal.pntd.0006442. eCollection 2018 Apr. PLoS Negl Trop Dis. 2018. PMID: 29702652 Free PMC article. Clinical Trial.
Evaluation of the safety and immunogenicity of the oral inactivated multivalent enterotoxigenic Escherichia coli vaccine ETVAX in Bangladeshi adults in a double-blind, randomized, placebo-controlled Phase I trial using electrochemiluminescence and ELISA assays for immunogenicity analyses.
Akhtar M, Chowdhury MI, Bhuiyan TR, Kaim J, Ahmed T, Rafique TA, Khan A, Rahman SIA, Khanam F, Begum YA, Sharif MZ, Islam LN, Carlin N, Maier N, Fix A, Wierzba TF, Walker RI, Bourgeois AL, Svennerholm AM, Qadri F, Lundgren A. Akhtar M, et al. Among authors: maier n. Vaccine. 2019 Sep 3;37(37):5645-5656. doi: 10.1016/j.vaccine.2018.11.040. Epub 2018 Nov 22. Vaccine. 2019. PMID: 30473185 Free PMC article. Clinical Trial.
A phase I trial of WRSS1, a Shigella sonnei live oral vaccine in Bangladeshi adults and children.
Raqib R, Sarker P, Zaman K, Alam NH, Wierzba TF, Maier N, Talukder K, Baqui AH, Suvarnapunya AE, Qadri F, Walker RI, Fix A, Venkatesan MM. Raqib R, et al. Among authors: maier n. Hum Vaccin Immunother. 2019;15(6):1326-1337. doi: 10.1080/21645515.2019.1575165. Epub 2019 Mar 19. Hum Vaccin Immunother. 2019. PMID: 30794051 Free PMC article. Clinical Trial.
Live attenuated enterotoxigenic Escherichia coli (ETEC) vaccine with dmLT adjuvant protects human volunteers against virulent experimental ETEC challenge.
Harro C, Louis Bourgeois A, Sack D, Walker R, DeNearing B, Brubaker J, Maier N, Fix A, Dally L, Chakraborty S, Clements JD, Saunders I, Darsley MJ. Harro C, et al. Among authors: maier n. Vaccine. 2019 Mar 28;37(14):1978-1986. doi: 10.1016/j.vaccine.2019.02.025. Epub 2019 Feb 21. Vaccine. 2019. PMID: 30797634 Free PMC article.
Safety and immunogenicity of the oral, inactivated, enterotoxigenic Escherichia coli vaccine ETVAX in Bangladeshi children and infants: a double-blind, randomised, placebo-controlled phase 1/2 trial.
Qadri F, Akhtar M, Bhuiyan TR, Chowdhury MI, Ahmed T, Rafique TA, Khan A, Rahman SIA, Khanam F, Lundgren A, Wiklund G, Kaim J, Löfstrand M, Carlin N, Bourgeois AL, Maier N, Fix A, Wierzba T, Walker RI, Svennerholm AM. Qadri F, et al. Among authors: maier n. Lancet Infect Dis. 2020 Feb;20(2):208-219. doi: 10.1016/S1473-3099(19)30571-7. Epub 2019 Nov 19. Lancet Infect Dis. 2020. PMID: 31757774 Free PMC article. Clinical Trial.
Safety and immunogenicity of intramuscularly administered CS6 subunit vaccine with a modified heat-labile enterotoxin from enterotoxigenic Escherichia coli.
Lee T, Gutiérrez RL, Maciel M, Poole S, Testa KJ, Trop S, Duplessis C, Lane A, Riddle MS, Hamer M, Alcala A, Prouty M, Maier N, Erdem R, Louis Bourgeois A, Porter CK. Lee T, et al. Among authors: maier n. Vaccine. 2021 Sep 15;39(39):5548-5556. doi: 10.1016/j.vaccine.2021.08.032. Epub 2021 Aug 18. Vaccine. 2021. PMID: 34419306 Free PMC article. Clinical Trial.
203 results