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PI3K activation in neural stem cells drives tumorigenesis which can be ameliorated by targeting the cAMP response element binding protein.
Daniel PM, Filiz G, Brown DV, Christie M, Waring PM, Zhang Y, Haynes JM, Pouton C, Flanagan D, Vincan E, Johns TG, Montgomery K, Phillips WA, Mantamadiotis T. Daniel PM, et al. Among authors: brown dv. Neuro Oncol. 2018 Sep 3;20(10):1344-1355. doi: 10.1093/neuonc/noy068. Neuro Oncol. 2018. PMID: 29718345 Free PMC article.
Zebrafish MITF-Low Melanoma Subtype Models Reveal Transcriptional Subclusters and MITF-Independent Residual Disease.
Travnickova J, Wojciechowska S, Khamseh A, Gautier P, Brown DV, Lefevre T, Brombin A, Ewing A, Capper A, Spitzer M, Dilshat R, Semple CA, Mathers ME, Lister JA, Steingrimsson E, Voet T, Ponting CP, Patton EE. Travnickova J, et al. Among authors: brown dv. Cancer Res. 2019 Nov 15;79(22):5769-5784. doi: 10.1158/0008-5472.CAN-19-0037. Epub 2019 Oct 3. Cancer Res. 2019. PMID: 31582381 Free PMC article.
Pregnane X-receptor promotes stem cell-mediated colon cancer relapse.
Planque C, Rajabi F, Grillet F, Finetti P, Bertucci F, Gironella M, Lozano JJ, Beucher B, Giraud J, Garambois V, Vincent C, Brown D, Caillo L, Kantar J, Pelegrin A, Prudhomme M, Ripoche J, Bourgaux JF, Ginestier C, Castells A, Hollande F, Pannequin J, Pascussi JM. Planque C, et al. Oncotarget. 2016 Aug 30;7(35):56558-56573. doi: 10.18632/oncotarget.10646. Oncotarget. 2016. PMID: 27448961 Free PMC article.
Type 1 conventional dendritic cell fate and function are controlled by DC-SCRIPT.
Zhang S, Coughlan HD, Ashayeripanah M, Seizova S, Kueh AJ, Brown DV, Cao W, Jacquelot N, D'Amico A, Lew AM, Zhan Y, Tonkin CJ, Villadangos JA, Smyth GK, Chopin M, Nutt SL. Zhang S, et al. Among authors: brown dv. Sci Immunol. 2021 Apr 2;6(58):eabf4432. doi: 10.1126/sciimmunol.abf4432. Sci Immunol. 2021. PMID: 33811060
61 results