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A two-step immunoassay for the simultaneous assessment of Aβ38, Aβ40 and Aβ42 in human blood plasma supports the Aβ42/Aβ40 ratio as a promising biomarker candidate of Alzheimer's disease.
Shahpasand-Kroner H, Klafki HW, Bauer C, Schuchhardt J, Hüttenrauch M, Stazi M, Bouter C, Wirths O, Vogelgsang J, Wiltfang J. Shahpasand-Kroner H, et al. Among authors: schuchhardt j. Alzheimers Res Ther. 2018 Dec 8;10(1):121. doi: 10.1186/s13195-018-0448-x. Alzheimers Res Ther. 2018. PMID: 30526652 Free PMC article.
Incremental value of biomarker combinations to predict progression of mild cognitive impairment to Alzheimer's dementia.
Frölich L, Peters O, Lewczuk P, Gruber O, Teipel SJ, Gertz HJ, Jahn H, Jessen F, Kurz A, Luckhaus C, Hüll M, Pantel J, Reischies FM, Schröder J, Wagner M, Rienhoff O, Wolf S, Bauer C, Schuchhardt J, Heuser I, Rüther E, Henn F, Maier W, Wiltfang J, Kornhuber J. Frölich L, et al. Among authors: schuchhardt j. Alzheimers Res Ther. 2017 Oct 10;9(1):84. doi: 10.1186/s13195-017-0301-7. Alzheimers Res Ther. 2017. PMID: 29017593 Free PMC article.
Diagnostic performance of automated plasma amyloid-β assays combined with pre-analytical immunoprecipitation.
Klafki HW, Vogelgsang J, Manuilova E, Bauer C, Jethwa A, Esselmann H, Jahn-Brodmann A, Osterloh D, Lachmann I, Breitling B, Rauter C, Hansen N, Bouter C, Palme S, Schuchhardt J, Wiltfang J. Klafki HW, et al. Among authors: schuchhardt j. Alzheimers Res Ther. 2022 Sep 7;14(1):127. doi: 10.1186/s13195-022-01071-y. Alzheimers Res Ther. 2022. PMID: 36071505 Free PMC article.
Don't forget about tau: the effects of ApoE4 genotype on Alzheimer's disease cerebrospinal fluid biomarkers in subjects with mild cognitive impairment-data from the Dementia Competence Network.
Benson GS, Bauer C, Hausner L, Couturier S, Lewczuk P, Peters O, Hüll M, Jahn H, Jessen F, Pantel J, Teipel SJ, Wagner M, Schuchhardt J, Wiltfang J, Kornhuber J, Frölich L. Benson GS, et al. Among authors: schuchhardt j. J Neural Transm (Vienna). 2022 Jun;129(5-6):477-486. doi: 10.1007/s00702-022-02461-0. Epub 2022 Jan 21. J Neural Transm (Vienna). 2022. PMID: 35061102 Free PMC article.
Identification of a Cascade of Changes in Activities of Daily Living Preceding Short-Term Clinical Deterioration in Mild Alzheimer's Disease Dementia via Lead-Lag Analysis.
Fuentes M, Klostermann A, Kleineidam L, Bauer C, Schuchhardt J, Maier W, Jessen F, Frölich L, Wiltfang J, Kornhuber J, Klöppel S, Schieting V, Teipel SJ, Wagner M, Peters O. Fuentes M, et al. Among authors: schuchhardt j. J Alzheimers Dis. 2020;76(3):1005-1015. doi: 10.3233/JAD-200230. J Alzheimers Dis. 2020. PMID: 32597807 Free PMC article.
60 results