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Engrafted parenchymal brain macrophages differ from microglia in transcriptome, chromatin landscape and response to challenge.
Shemer A, Grozovski J, Tay TL, Tao J, Volaski A, Süß P, Ardura-Fabregat A, Gross-Vered M, Kim JS, David E, Chappell-Maor L, Thielecke L, Glass CK, Cornils K, Prinz M, Jung S. Shemer A, et al. Among authors: kim js. Nat Commun. 2018 Dec 6;9(1):5206. doi: 10.1038/s41467-018-07548-5. Nat Commun. 2018. PMID: 30523248 Free PMC article.
Graft-versus-host disease of the CNS is mediated by TNF upregulation in microglia.
Mathew NR, Vinnakota JM, Apostolova P, Erny D, Hamarsheh S, Andrieux G, Kim JS, Hanke K, Goldmann T, Chappell-Maor L, El-Khawanky N, Ihorst G, Schmidt D, Duyster J, Finke J, Blank T, Boerries M, Blazar BR, Jung S, Prinz M, Zeiser R. Mathew NR, et al. Among authors: kim js. J Clin Invest. 2020 Mar 2;130(3):1315-1329. doi: 10.1172/JCI130272. J Clin Invest. 2020. PMID: 31846439 Free PMC article.
Interleukin-10 Prevents Pathological Microglia Hyperactivation following Peripheral Endotoxin Challenge.
Shemer A, Scheyltjens I, Frumer GR, Kim JS, Grozovski J, Ayanaw S, Dassa B, Van Hove H, Chappell-Maor L, Boura-Halfon S, Leshkowitz D, Mueller W, Maggio N, Movahedi K, Jung S. Shemer A, et al. Among authors: kim js. Immunity. 2020 Nov 17;53(5):1033-1049.e7. doi: 10.1016/j.immuni.2020.09.018. Epub 2020 Oct 12. Immunity. 2020. PMID: 33049219 Free article.
A Binary Cre Transgenic Approach Dissects Microglia and CNS Border-Associated Macrophages.
Kim JS, Kolesnikov M, Peled-Hajaj S, Scheyltjens I, Xia Y, Trzebanski S, Haimon Z, Shemer A, Lubart A, Van Hove H, Chappell-Maor L, Boura-Halfon S, Movahedi K, Blinder P, Jung S. Kim JS, et al. Immunity. 2021 Jan 12;54(1):176-190.e7. doi: 10.1016/j.immuni.2020.11.007. Epub 2020 Dec 16. Immunity. 2021. PMID: 33333014 Free article.
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