Canavan M - Search Results

1

Enriched Cd141+ DCs in the joint are transcriptionally distinct, activated, and contribute to joint pathogenesis.

Canavan M, Walsh AM, Bhargava V, Wade SM, McGarry T, Marzaioli V, Moran B, Biniecka M, Convery H, Wade S, Orr C, Mullan R, Fletcher JM, Nagpal S, Veale DJ, Fearon U. Canavan M, et al. JCI Insight. 2018 Dec 6;3(23):e95228. doi: 10.1172/jci.insight.95228. JCI Insight. 2018. PMID: 30518680 Free PMC article.

2

Polyfunctional, Pathogenic CD161+ Th17 Lineage Cells Are Resistant to Regulatory T Cell-Mediated Suppression in the Context of Autoimmunity.

Basdeo SA, Moran B, Cluxton D, Canavan M, McCormick J, Connolly M, Orr C, Mills KH, Veale DJ, Fearon U, Fletcher JM. Basdeo SA, et al. Among authors: canavan m. J Immunol. 2015 Jul 15;195(2):528-40. doi: 10.4049/jimmunol.1402990. Epub 2015 Jun 10. J Immunol. 2015. PMID: 26062995

3

Dysregulated bioenergetics: a key regulator of joint inflammation.

Biniecka M, Canavan M, McGarry T, Gao W, McCormick J, Cregan S, Gallagher L, Smith T, Phelan JJ, Ryan J, O'Sullivan J, Ng CT, Veale DJ, Fearon U. Biniecka M, et al. Among authors: canavan m. Ann Rheum Dis. 2016 Dec;75(12):2192-2200. doi: 10.1136/annrheumdis-2015-208476. Epub 2016 Mar 24. Ann Rheum Dis. 2016. PMID: 27013493 Free PMC article.

4

Hypoxia, mitochondrial dysfunction and synovial invasiveness in rheumatoid arthritis.

Fearon U, Canavan M, Biniecka M, Veale DJ. Fearon U, et al. Among authors: canavan m. Nat Rev Rheumatol. 2016 Jul;12(7):385-97. doi: 10.1038/nrrheum.2016.69. Epub 2016 May 26. Nat Rev Rheumatol. 2016. PMID: 27225300 Review.

5

Ex-Th17 (Nonclassical Th1) Cells Are Functionally Distinct from Classical Th1 and Th17 Cells and Are Not Constrained by Regulatory T Cells.

Basdeo SA, Cluxton D, Sulaimani J, Moran B, Canavan M, Orr C, Veale DJ, Fearon U, Fletcher JM. Basdeo SA, et al. Among authors: canavan m. J Immunol. 2017 Mar 15;198(6):2249-2259. doi: 10.4049/jimmunol.1600737. Epub 2017 Feb 6. J Immunol. 2017. PMID: 28167631

6

Resolution of TLR2-induced inflammation through manipulation of metabolic pathways in Rheumatoid Arthritis.

McGarry T, Biniecka M, Gao W, Cluxton D, Canavan M, Wade S, Wade S, Gallagher L, Orr C, Veale DJ, Fearon U. McGarry T, et al. Among authors: canavan m. Sci Rep. 2017 Feb 22;7:43165. doi: 10.1038/srep43165. Sci Rep. 2017. PMID: 28225071 Free PMC article.

7

CD40L-Dependent Pathway Is Active at Various Stages of Rheumatoid Arthritis Disease Progression.

Guo Y, Walsh AM, Fearon U, Smith MD, Wechalekar MD, Yin X, Cole S, Orr C, McGarry T, Canavan M, Kelly S, Lin TA, Liu X, Proudman SM, Veale DJ, Pitzalis C, Nagpal S. Guo Y, et al. Among authors: canavan m. J Immunol. 2017 Jun 1;198(11):4490-4501. doi: 10.4049/jimmunol.1601988. Epub 2017 Apr 28. J Immunol. 2017. PMID: 28455435

8

Immune checkpoint inhibitor PD-1 pathway is down-regulated in synovium at various stages of rheumatoid arthritis disease progression.

Guo Y, Walsh AM, Canavan M, Wechalekar MD, Cole S, Yin X, Scott B, Loza M, Orr C, McGarry T, Bombardieri M, Humby F, Proudman SM, Pitzalis C, Smith MD, Friedman JR, Anderson I, Madakamutil L, Veale DJ, Fearon U, Nagpal S. Guo Y, et al. Among authors: canavan m. PLoS One. 2018 Feb 28;13(2):e0192704. doi: 10.1371/journal.pone.0192704. eCollection 2018. PLoS One. 2018. PMID: 29489833 Free PMC article.

9

The pathogenic role of dendritic cells in non-infectious anterior uveitis.

O'Rourke M, Fearon U, Sweeney CM, Basdeo SA, Fletcher JM, Murphy CC, Canavan M. O'Rourke M, et al. Among authors: canavan m. Exp Eye Res. 2018 Aug;173:121-128. doi: 10.1016/j.exer.2018.05.008. Epub 2018 May 25. Exp Eye Res. 2018. PMID: 29763582

10

Altered expression of microRNA-23a in psoriatic arthritis modulates synovial fibroblast pro-inflammatory mechanisms via phosphodiesterase 4B.

Wade SM, Trenkmann M, McGarry T, Canavan M, Marzaioli V, Wade SC, Veale DJ, Fearon U. Wade SM, et al. Among authors: canavan m. J Autoimmun. 2019 Jan;96:86-93. doi: 10.1016/j.jaut.2018.08.008. Epub 2018 Sep 1. J Autoimmun. 2019. PMID: 30181004 Free article.

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