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Page 1
Nonlinear Mixed-Effects Model of Z-Endoxifen Concentrations in Tamoxifen-Treated Patients from the CEPAM Cohort.
Mc Laughlin AM, Helland T, Klima F, Koolen SLW, van Schaik RHN, Mathijssen RHJ, Neven P, Swen JJ, Guchelaar HJ, Dalenc F, White-Koning M, Michelet R, Mikus G, Schroth W, Mürdter T, Brauch H, Schwab M, Søiland H, Mellgren G, Thomas F, Kloft C, Hertz DL; CYP2D6 Endoxifen Percentage Activity Model (CEPAM) Consortium. Mc Laughlin AM, et al. Among authors: michelet r. Clin Pharmacol Ther. 2024 Sep;116(3):690-702. doi: 10.1002/cpt.3238. Epub 2024 Mar 18. Clin Pharmacol Ther. 2024. PMID: 38494911
A quantitative modeling framework to understand the physiology of the hypothalamic-pituitary-adrenal axis and interaction with cortisol replacement therapy.
Bindellini D, Michelet R, Aulin LBS, Melin J, Neumann U, Blankenstein O, Huisinga W, Whitaker MJ, Ross R, Kloft C. Bindellini D, et al. Among authors: michelet r. J Pharmacokinet Pharmacodyn. 2024 Dec;51(6):809-824. doi: 10.1007/s10928-024-09934-7. Epub 2024 Jul 8. J Pharmacokinet Pharmacodyn. 2024. PMID: 38977635 Free PMC article.
Barriers to global pharmacometrics: educational challenges and opportunities across the globe.
Michelet R, Aulin LBS, Borghardt JM, Costa TD, Denti P, Ibarra M, Ma G, Meibohm B, Pillai GC, Schmidt S, Hennig S, Kloft C. Michelet R, et al. CPT Pharmacometrics Syst Pharmacol. 2023 Jun;12(6):743-747. doi: 10.1002/psp4.12940. Epub 2023 Mar 24. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 36960632 Free PMC article. No abstract available.
Population pharmacokinetics of TLD-1, a novel liposomal doxorubicin, in a phase I trial.
Mc Laughlin AM, Hess D, Michelet R, Colombo I, Haefliger S, Bastian S, Rabaglio M, Schwitter M, Fischer S, Eckhardt K, Hayoz S, Kopp C, Klose M, Sessa C, Stathis A, Halbherr S, Huisinga W, Joerger M, Kloft C. Mc Laughlin AM, et al. Among authors: michelet r. Cancer Chemother Pharmacol. 2024 Sep;94(3):349-360. doi: 10.1007/s00280-024-04679-z. Epub 2024 Jun 15. Cancer Chemother Pharmacol. 2024. PMID: 38878207 Free PMC article. Clinical Trial.
Model-Informed Target Morning 17α-Hydroxyprogesterone Concentrations in Dried Blood Spots for Pediatric Congenital Adrenal Hyperplasia Patients.
Stachanow V, Neumann U, Blankenstein O, Alder-Baerens N, Bindellini D, Hindmarsh P, Ross RJ, Whitaker MJ, Melin J, Huisinga W, Michelet R, Kloft C. Stachanow V, et al. Among authors: michelet r. Pharmaceuticals (Basel). 2023 Mar 21;16(3):464. doi: 10.3390/ph16030464. Pharmaceuticals (Basel). 2023. PMID: 36986563 Free PMC article.
Physiologically Based Pharmacokinetic Predictions of Tramadol Exposure Throughout Pediatric Life: an Analysis of the Different Clearance Contributors with Emphasis on CYP2D6 Maturation.
T'jollyn H, Snoeys J, Vermeulen A, Michelet R, Cuyckens F, Mannens G, Van Peer A, Annaert P, Allegaert K, Van Bocxlaer J, Boussery K. T'jollyn H, et al. Among authors: michelet r. AAPS J. 2015 Nov;17(6):1376-87. doi: 10.1208/s12248-015-9803-z. Epub 2015 Jul 25. AAPS J. 2015. PMID: 26209290 Free PMC article.
68 results