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RAS in FGF23: another piece in the puzzle.
Ovejero D, Collins MT. Ovejero D, et al. J Clin Endocrinol Metab. 2014 Jan;99(1):63-6. doi: 10.1210/jc.2013-4290. J Clin Endocrinol Metab. 2014. PMID: 24384015 Free PMC article. No abstract available.
Expression of an active Gαs mutant in skeletal stem cells is sufficient and necessary for fibrous dysplasia initiation and maintenance.
Zhao X, Deng P, Iglesias-Bartolome R, Amornphimoltham P, Steffen DJ, Jin Y, Molinolo AA, de Castro LF, Ovejero D, Yuan Q, Chen Q, Han X, Bai D, Taylor SS, Yang Y, Collins MT, Gutkind JS. Zhao X, et al. Among authors: ovejero d. Proc Natl Acad Sci U S A. 2018 Jan 16;115(3):E428-E437. doi: 10.1073/pnas.1713710115. Epub 2017 Dec 27. Proc Natl Acad Sci U S A. 2018. PMID: 29282319 Free PMC article.
Multilineage somatic activating mutations in HRAS and NRAS cause mosaic cutaneous and skeletal lesions, elevated FGF23 and hypophosphatemia.
Lim YH, Ovejero D, Sugarman JS, Deklotz CM, Maruri A, Eichenfield LF, Kelley PK, Jüppner H, Gottschalk M, Tifft CJ, Gafni RI, Boyce AM, Cowen EW, Bhattacharyya N, Guthrie LC, Gahl WA, Golas G, Loring EC, Overton JD, Mane SM, Lifton RP, Levy ML, Collins MT, Choate KA. Lim YH, et al. Among authors: ovejero d. Hum Mol Genet. 2014 Jan 15;23(2):397-407. doi: 10.1093/hmg/ddt429. Epub 2013 Sep 4. Hum Mol Genet. 2014. PMID: 24006476 Free PMC article.
23 results