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Somatic Mutations Reveal Lineage Relationships and Age-Related Mutagenesis in Human Hematopoiesis.
Cell Rep. 2018 Nov 27;25(9):2308-2316.e4. doi: 10.1016/j.celrep.2018.11.014.
Cell Rep. 2018.
PMID: 30485801
Free PMC article.
Mutation accumulation and developmental lineages in normal and Down syndrome human fetal haematopoiesis.
Hasaart KAL, Manders F, van der Hoorn ML, Verheul M, Poplonski T, Kuijk E, de Sousa Lopes SMC, van Boxtel R.
Hasaart KAL, et al.
Sci Rep. 2020 Jul 31;10(1):12991. doi: 10.1038/s41598-020-69822-1.
Sci Rep. 2020.
PMID: 32737409
Free PMC article.
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Human induced pluripotent stem cells display a similar mutation burden as embryonic pluripotent cells in vivo.
Hasaart KAL, Manders F, Ubels J, Verheul M, van Roosmalen MJ, Groenen NM, Oka R, Kuijk E, Lopes SMCS, Boxtel RV.
Hasaart KAL, et al.
iScience. 2022 Jan 6;25(2):103736. doi: 10.1016/j.isci.2022.103736. eCollection 2022 Feb 18.
iScience. 2022.
PMID: 35118356
Free PMC article.
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Increased risk of leukaemia in children with Down syndrome: a somatic evolutionary view.
Hasaart KAL, Bertrums EJM, Manders F, Goemans BF, van Boxtel R.
Hasaart KAL, et al.
Expert Rev Mol Med. 2021 Apr 27;23:e5. doi: 10.1017/erm.2021.6.
Expert Rev Mol Med. 2021.
PMID: 33902785
Free PMC article.
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