Ryan MT - Search Results

1

VDAC2 enables BAX to mediate apoptosis and limit tumor development.

Chin HS, Li MX, Tan IKL, Ninnis RL, Reljic B, Scicluna K, Dagley LF, Sandow JJ, Kelly GL, Samson AL, Chappaz S, Khaw SL, Chang C, Morokoff A, Brinkmann K, Webb A, Hockings C, Hall CM, Kueh AJ, Ryan MT, Kluck RM, Bouillet P, Herold MJ, Gray DHD, Huang DCS, van Delft MF, Dewson G. Chin HS, et al. Among authors: ryan mt. Nat Commun. 2018 Nov 26;9(1):4976. doi: 10.1038/s41467-018-07309-4. Nat Commun. 2018. PMID: 30478310 Free PMC article.

2

Inhibition of Bak activation by VDAC2 is dependent on the Bak transmembrane anchor.

Lazarou M, Stojanovski D, Frazier AE, Kotevski A, Dewson G, Craigen WJ, Kluck RM, Vaux DL, Ryan MT. Lazarou M, et al. Among authors: ryan mt. J Biol Chem. 2010 Nov 19;285(47):36876-83. doi: 10.1074/jbc.M110.159301. Epub 2010 Sep 17. J Biol Chem. 2010. PMID: 20851889 Free PMC article.

3

Assembly of the Bak apoptotic pore: a critical role for the Bak protein α6 helix in the multimerization of homodimers during apoptosis.

Ma S, Hockings C, Anwari K, Kratina T, Fennell S, Lazarou M, Ryan MT, Kluck RM, Dewson G. Ma S, et al. Among authors: ryan mt. J Biol Chem. 2013 Sep 6;288(36):26027-26038. doi: 10.1074/jbc.M113.490094. Epub 2013 Jul 26. J Biol Chem. 2013. PMID: 23893415 Free PMC article.

4

Bax targets mitochondria by distinct mechanisms before or during apoptotic cell death: a requirement for VDAC2 or Bak for efficient Bax apoptotic function.

Ma SB, Nguyen TN, Tan I, Ninnis R, Iyer S, Stroud DA, Menard M, Kluck RM, Ryan MT, Dewson G. Ma SB, et al. Among authors: ryan mt. Cell Death Differ. 2014 Dec;21(12):1925-35. doi: 10.1038/cdd.2014.119. Epub 2014 Aug 22. Cell Death Differ. 2014. PMID: 25146925 Free PMC article.

5

Accessory subunits are integral for assembly and function of human mitochondrial complex I.

Stroud DA, Surgenor EE, Formosa LE, Reljic B, Frazier AE, Dibley MG, Osellame LD, Stait T, Beilharz TH, Thorburn DR, Salim A, Ryan MT. Stroud DA, et al. Among authors: ryan mt. Nature. 2016 Oct 6;538(7623):123-126. doi: 10.1038/nature19754. Epub 2016 Sep 14. Nature. 2016. PMID: 27626371

6

BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis.

McArthur K, Whitehead LW, Heddleston JM, Li L, Padman BS, Oorschot V, Geoghegan ND, Chappaz S, Davidson S, San Chin H, Lane RM, Dramicanin M, Saunders TL, Sugiana C, Lessene R, Osellame LD, Chew TL, Dewson G, Lazarou M, Ramm G, Lessene G, Ryan MT, Rogers KL, van Delft MF, Kile BT. McArthur K, et al. Among authors: ryan mt. Science. 2018 Feb 23;359(6378):eaao6047. doi: 10.1126/science.aao6047. Science. 2018. PMID: 29472455

7

Kamerkar SC, Kraus F, Sharpe AJ, Pucadyil TJ, Ryan MT. Kamerkar SC, et al. Among authors: ryan mt. Nat Commun. 2018 Dec 7;9(1):5239. doi: 10.1038/s41467-018-07543-w. Nat Commun. 2018. PMID: 30531964 Free PMC article.

8

The Mitochondrial Acyl-carrier Protein Interaction Network Highlights Important Roles for LYRM Family Members in Complex I and Mitoribosome Assembly.

Dibley MG, Formosa LE, Lyu B, Reljic B, McGann D, Muellner-Wong L, Kraus F, Sharpe AJ, Stroud DA, Ryan MT. Dibley MG, et al. Among authors: ryan mt. Mol Cell Proteomics. 2020 Jan;19(1):65-77. doi: 10.1074/mcp.RA119.001784. Epub 2019 Oct 30. Mol Cell Proteomics. 2020. PMID: 31666358 Free PMC article.

9

HIGD2A is Required for Assembly of the COX3 Module of Human Mitochondrial Complex IV.

Hock DH, Reljic B, Ang CS, Muellner-Wong L, Mountford HS, Compton AG, Ryan MT, Thorburn DR, Stroud DA. Hock DH, et al. Among authors: ryan mt. Mol Cell Proteomics. 2020 Jul;19(7):1145-1160. doi: 10.1074/mcp.RA120.002076. Epub 2020 Apr 21. Mol Cell Proteomics. 2020. PMID: 32317297 Free PMC article.

10

Dissecting the Roles of Mitochondrial Complex I Intermediate Assembly Complex Factors in the Biogenesis of Complex I.

Formosa LE, Muellner-Wong L, Reljic B, Sharpe AJ, Jackson TD, Beilharz TH, Stojanovski D, Lazarou M, Stroud DA, Ryan MT. Formosa LE, et al. Among authors: ryan mt. Cell Rep. 2020 Apr 21;31(3):107541. doi: 10.1016/j.celrep.2020.107541. Cell Rep. 2020. PMID: 32320651 Free article.

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