Baardsnes J - Search Results

1

Enhanced anti-metastatic bioactivity of an IGF-TRAP re-engineered to improve physicochemical properties.

Vaniotis G, Moffett S, Sulea T, Wang N, Elahi SM, Lessard E, Baardsnes J, Perrino S, Durocher Y, Frystyk J, Massie B, Brodt P. Vaniotis G, et al. Among authors: baardsnes j. Sci Rep. 2018 Nov 26;8(1):17361. doi: 10.1038/s41598-018-35407-2. Sci Rep. 2018. PMID: 30478273 Free PMC article.

2

Engineering and therapeutic application of single-chain bivalent TGF-β family traps.

Zwaagstra JC, Sulea T, Baardsnes J, Lenferink AE, Collins C, Cantin C, Paul-Roc B, Grothe S, Hossain S, Richer LP, L'Abbé D, Tom R, Cass B, Durocher Y, O'Connor-McCourt MD. Zwaagstra JC, et al. Among authors: baardsnes j. Mol Cancer Ther. 2012 Jul;11(7):1477-87. doi: 10.1158/1535-7163.MCT-12-0060. Epub 2012 May 4. Mol Cancer Ther. 2012. PMID: 22562986

3

Assisted Design of Antibody and Protein Therapeutics (ADAPT).

Vivcharuk V, Baardsnes J, Deprez C, Sulea T, Jaramillo M, Corbeil CR, Mullick A, Magoon J, Marcil A, Durocher Y, O'Connor-McCourt MD, Purisima EO. Vivcharuk V, et al. Among authors: baardsnes j. PLoS One. 2017 Jul 27;12(7):e0181490. doi: 10.1371/journal.pone.0181490. eCollection 2017. PLoS One. 2017. PMID: 28750054 Free PMC article.

4

Redesigning an antibody H3 loop by virtual screening of a small library of human germline-derived sequences.

Corbeil CR, Manenda MS, Sulea T, Baardsnes J, Picard MÈ, Hogues H, Gaudreault F, Deprez C, Shi R, Purisima EO. Corbeil CR, et al. Among authors: baardsnes j. Sci Rep. 2021 Nov 1;11(1):21362. doi: 10.1038/s41598-021-00669-w. Sci Rep. 2021. PMID: 34725391 Free PMC article.

5

Production of afucosylated antibodies in CHO cells by coexpression of an anti-FUT8 intrabody.

Joubert S, Guimond J, Perret S, Malenfant F, Elahi SM, Marcil A, Parat M, Gilbert M, Lenferink AEG, Baardsnes J, Durocher Y. Joubert S, et al. Among authors: baardsnes j. Biotechnol Bioeng. 2022 Aug;119(8):2206-2220. doi: 10.1002/bit.28127. Epub 2022 May 14. Biotechnol Bioeng. 2022. PMID: 35509261

6

Escherichia coli expression and refolding of E/K-coil-tagged EGF generates fully bioactive EGF for diverse applications.

Le PU, Lenferink AE, Pinard M, Baardsnes J, Massie B, O'Connor-McCourt MD. Le PU, et al. Among authors: baardsnes j. Protein Expr Purif. 2009 Apr;64(2):108-17. doi: 10.1016/j.pep.2008.11.005. Epub 2008 Nov 25. Protein Expr Purif. 2009. PMID: 19061959

7

Structure-based engineering of pH-dependent antibody binding for selective targeting of solid-tumor microenvironment.

Sulea T, Rohani N, Baardsnes J, Corbeil CR, Deprez C, Cepero-Donates Y, Robert A, Schrag JD, Parat M, Duchesne M, Jaramillo ML, Purisima EO, Zwaagstra JC. Sulea T, et al. Among authors: baardsnes j. MAbs. 2020 Jan-Dec;12(1):1682866. doi: 10.1080/19420862.2019.1682866. MAbs. 2020. PMID: 31777319 Free PMC article.

8

Binding and functional profiling of antibody mutants guides selection of optimal candidates as antibody drug conjugates.

Zwaagstra JC, Sulea T, Baardsnes J, Radinovic S, Cepero-Donates Y, Robert A, O'Connor-McCourt MD, Tikhomirov IA, Jaramillo ML. Zwaagstra JC, et al. Among authors: baardsnes j. PLoS One. 2019 Dec 31;14(12):e0226593. doi: 10.1371/journal.pone.0226593. eCollection 2019. PLoS One. 2019. PMID: 31891584 Free PMC article.

9

Structure-based dual affinity optimization of a SARS-CoV-1/2 cross-reactive single-domain antibody.

Sulea T, Baardsnes J, Stuible M, Rohani N, Tran A, Parat M, Cepero Donates Y, Duchesne M, Plante P, Kour G, Durocher Y. Sulea T, et al. Among authors: baardsnes j. PLoS One. 2022 Mar 30;17(3):e0266250. doi: 10.1371/journal.pone.0266250. eCollection 2022. PLoS One. 2022. PMID: 35353868 Free PMC article.

10

Optimization of a high-cell-density polyethylenimine transfection method for rapid protein production in CHO-EBNA1 cells.

Stuible M, Burlacu A, Perret S, Brochu D, Paul-Roc B, Baardsnes J, Loignon M, Grazzini E, Durocher Y. Stuible M, et al. Among authors: baardsnes j. J Biotechnol. 2018 Sep 10;281:39-47. doi: 10.1016/j.jbiotec.2018.06.307. Epub 2018 Jun 7. J Biotechnol. 2018. PMID: 29886030

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