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Rapamycin improves healthspan but not inflammaging in nfκb1-/- mice.
Correia-Melo C, Birch J, Fielder E, Rahmatika D, Taylor J, Chapman J, Lagnado A, Carroll BM, Miwa S, Richardson G, Jurk D, Oakley F, Mann J, Mann DA, Korolchuk VI, Passos JF. Correia-Melo C, et al. Among authors: richardson g. Aging Cell. 2019 Feb;18(1):e12882. doi: 10.1111/acel.12882. Epub 2018 Nov 23. Aging Cell. 2019. PMID: 30468013 Free PMC article.
New Horizons in cellular senescence for clinicians.
Witham MD, Granic A, Miwa S, Passos JF, Richardson GD, Sayer AA. Witham MD, et al. Age Ageing. 2023 Jul 1;52(7):afad127. doi: 10.1093/ageing/afad127. Age Ageing. 2023. PMID: 37466640 Free PMC article.
Suppressed basal mitophagy drives cellular aging phenotypes that can be reversed by a p62-targeting small molecule.
Kelly G, Kataura T, Panek J, Ma G, Salmonowicz H, Davis A, Kendall H, Brookes C, Ayine-Tora DM, Banks P, Nelson G, Dobby L, Pitrez PR, Booth L, Costello L, Richardson GD, Lovat P, Przyborski S, Ferreira L, Greaves L, Szczepanowska K, von Zglinicki T, Miwa S, Brown M, Flagler M, Oblong JE, Bascom CC, Carroll B, Reynisson J, Korolchuk VI. Kelly G, et al. Among authors: richardson gd. Dev Cell. 2024 Aug 5;59(15):1924-1939.e7. doi: 10.1016/j.devcel.2024.04.020. Epub 2024 Jun 18. Dev Cell. 2024. PMID: 38897197 Free article.
Anthracycline-induced cardiotoxicity and senescence.
Booth LK, Redgrave RE, Folaranmi O, Gill JH, Richardson GD. Booth LK, et al. Front Aging. 2022 Nov 14;3:1058435. doi: 10.3389/fragi.2022.1058435. eCollection 2022. Front Aging. 2022. PMID: 36452034 Free PMC article. Review.
Activation of telomerase by TA-65 enhances immunity and reduces inflammation post myocardial infarction.
Bawamia B, Spray L, Wangsaputra VK, Bennaceur K, Vahabi S, Stellos K, Kharatikoopaei E, Ogundimu E, Gale CP, Keavney B, Maier R, Hancock H, Richardson G, Austin D, Spyridopoulos I. Bawamia B, et al. Among authors: richardson g. Geroscience. 2023 Aug;45(4):2689-2705. doi: 10.1007/s11357-023-00794-6. Epub 2023 Apr 22. Geroscience. 2023. PMID: 37086366 Free PMC article. Clinical Trial.
Effector T cell chemokine IP-10 predicts cardiac recovery and clinical outcomes post-myocardial infarction.
Sopova K, Tual-Chalot S, Mueller-Hennessen M, Vlachogiannis NI, Georgiopoulos G, Biener M, Sachse M, Turchinovich A, Polycarpou-Schwarz M, Spray L, Maneta E, Bennaceur K, Mohammad A, Richardson GD, Gatsiou A, Langer HF, Frey N, Stamatelopoulos K, Heineke J, Duerschmied D, Giannitsis E, Spyridopoulos I, Stellos K. Sopova K, et al. Among authors: richardson gd. Front Immunol. 2023 Jun 22;14:1177467. doi: 10.3389/fimmu.2023.1177467. eCollection 2023. Front Immunol. 2023. PMID: 37426649 Free PMC article.
1,218 results