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Maximizing in vivo target clearance by design of pH-dependent target binding antibodies with altered affinity to FcRn.
Yang D, Giragossian C, Castellano S, Lasaro M, Xiao H, Saraf H, Hess Kenny C, Rybina I, Huang ZF, Ahlberg J, Bigwarfe T, Myzithras M, Waltz E, Roberts S, Kroe-Barrett R, Singh S. Yang D, et al. Among authors: myzithras m. MAbs. 2017 Oct;9(7):1105-1117. doi: 10.1080/19420862.2017.1359455. Epub 2017 Aug 8. MAbs. 2017. PMID: 28786732 Free PMC article.
Retrospective analysis of model-based predictivity of human pharmacokinetics for anti-IL-36R monoclonal antibody MAB92 using a rat anti-mouse IL-36R monoclonal antibody and RNA expression data (FANTOM5).
Ahlberg J, Giragossian C, Li H, Myzithras M, Raymond E, Caviness G, Grimaldi C, Brown SE, Perez R, Yang D, Kroe-Barrett R, Joseph D, Pamulapati C, Coble K, Ruus P, Woska JR, Ganesan R, Hansel S, Mbow ML. Ahlberg J, et al. Among authors: myzithras m. MAbs. 2019 Jul;11(5):956-964. doi: 10.1080/19420862.2019.1615345. Epub 2019 Jun 4. MAbs. 2019. PMID: 31068073 Free PMC article.
11 results