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Cell-free DNA profiling of metastatic prostate cancer reveals microsatellite instability, structural rearrangements and clonal hematopoiesis.
Mayrhofer M, De Laere B, Whitington T, Van Oyen P, Ghysel C, Ampe J, Ost P, Demey W, Hoekx L, Schrijvers D, Brouwers B, Lybaert W, Everaert E, De Maeseneer D, Strijbos M, Bols A, Fransis K, Oeyen S, van Dam PJ, Van den Eynden G, Rutten A, Aly M, Nordström T, Van Laere S, Rantalainen M, Rajan P, Egevad L, Ullén A, Yachnin J, Dirix L, Grönberg H, Lindberg J. Mayrhofer M, et al. Among authors: yachnin j. Genome Med. 2018 Nov 21;10(1):85. doi: 10.1186/s13073-018-0595-5. Genome Med. 2018. PMID: 30458854 Free PMC article.
Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullén A, Yachnin J, Nilsson S, Panaretakis T. Kharaziha P, et al. Among authors: yachnin j. Oncotarget. 2015 Aug 28;6(25):21740-54. doi: 10.18632/oncotarget.3226. Oncotarget. 2015. PMID: 25844599 Free PMC article. Clinical Trial.
The In Vitro Stability of Circulating Tumour DNA.
Henao Diaz E, Yachnin J, Grönberg H, Lindberg J. Henao Diaz E, et al. Among authors: yachnin j. PLoS One. 2016 Dec 13;11(12):e0168153. doi: 10.1371/journal.pone.0168153. eCollection 2016. PLoS One. 2016. PMID: 27959945 Free PMC article.
TP53 Outperforms Other Androgen Receptor Biomarkers to Predict Abiraterone or Enzalutamide Outcome in Metastatic Castration-Resistant Prostate Cancer.
De Laere B, Oeyen S, Mayrhofer M, Whitington T, van Dam PJ, Van Oyen P, Ghysel C, Ampe J, Ost P, Demey W, Hoekx L, Schrijvers D, Brouwers B, Lybaert W, Everaert EG, De Maeseneer D, Strijbos M, Bols A, Fransis K, Beije N, de Kruijff IE, van Dam V, Brouwer A, Goossens D, Heyrman L, Van den Eynden GG, Rutten A, Del Favero J, Rantalainen M, Rajan P, Sleijfer S, Ullén A, Yachnin J, Grönberg H, Van Laere SJ, Lindberg J, Dirix LY. De Laere B, et al. Among authors: yachnin j. Clin Cancer Res. 2019 Mar 15;25(6):1766-1773. doi: 10.1158/1078-0432.CCR-18-1943. Epub 2018 Sep 12. Clin Cancer Res. 2019. PMID: 30209161 Free PMC article. Clinical Trial.
Early alkaline phosphatase dynamics as biomarker of survival in metastatic castration-resistant prostate cancer patients treated with radium-223.
van der Doelen MJ, Stockhaus A, Ma Y, Mehra N, Yachnin J, Gerritsen WR, Nilsson S, van Oort IM, Ullén A. van der Doelen MJ, et al. Among authors: yachnin j. Eur J Nucl Med Mol Imaging. 2021 Sep;48(10):3325-3334. doi: 10.1007/s00259-021-05283-6. Epub 2021 Mar 8. Eur J Nucl Med Mol Imaging. 2021. PMID: 33686456 Free PMC article.
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