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Spec-seq unveils transcriptional subpopulations of antibody-secreting cells following influenza vaccination.
Neu KE, Guthmiller JJ, Huang M, La J, Vieira MC, Kim K, Zheng NY, Cortese M, Tepora ME, Hamel NJ, Rojas KT, Henry C, Shaw D, Dulberger CL, Pulendran B, Cobey S, Khan AA, Wilson PC. Neu KE, et al. Among authors: hamel nj. J Clin Invest. 2019 Jan 2;129(1):93-105. doi: 10.1172/JCI121341. Epub 2018 Nov 19. J Clin Invest. 2019. PMID: 30457979 Free PMC article.
Polyreactive Broadly Neutralizing B cells Are Selected to Provide Defense against Pandemic Threat Influenza Viruses.
Guthmiller JJ, Lan LY, Fernández-Quintero ML, Han J, Utset HA, Bitar DJ, Hamel NJ, Stovicek O, Li L, Tepora M, Henry C, Neu KE, Dugan HL, Borowska MT, Chen YQ, Liu STH, Stamper CT, Zheng NY, Huang M, Palm AE, García-Sastre A, Nachbagauer R, Palese P, Coughlan L, Krammer F, Ward AB, Liedl KR, Wilson PC. Guthmiller JJ, et al. Among authors: hamel nj. Immunity. 2020 Dec 15;53(6):1230-1244.e5. doi: 10.1016/j.immuni.2020.10.005. Epub 2020 Oct 22. Immunity. 2020. PMID: 33096040 Free PMC article.
First exposure to the pandemic H1N1 virus induced broadly neutralizing antibodies targeting hemagglutinin head epitopes.
Guthmiller JJ, Han J, Li L, Freyn AW, Liu STH, Stovicek O, Stamper CT, Dugan HL, Tepora ME, Utset HA, Bitar DJ, Hamel NJ, Changrob S, Zheng NY, Huang M, Krammer F, Nachbagauer R, Palese P, Ward AB, Wilson PC. Guthmiller JJ, et al. Among authors: hamel nj. Sci Transl Med. 2021 Jun 2;13(596):eabg4535. doi: 10.1126/scitranslmed.abg4535. Sci Transl Med. 2021. PMID: 34078743 Free PMC article.