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Endothelial cell rearrangements during vascular patterning require PI3-kinase-mediated inhibition of actomyosin contractility.
Angulo-Urarte A, Casado P, Castillo SD, Kobialka P, Kotini MP, Figueiredo AM, Castel P, Rajeeve V, Milà-Guasch M, Millan J, Wiesner C, Serra H, Muixi L, Casanovas O, Viñals F, Affolter M, Gerhardt H, Huveneers S, Belting HG, Cutillas PR, Graupera M. Angulo-Urarte A, et al. Among authors: rajeeve v. Nat Commun. 2018 Nov 16;9(1):4826. doi: 10.1038/s41467-018-07172-3. Nat Commun. 2018. PMID: 30446640 Free PMC article.
Knockout of the PKN Family of Rho Effector Kinases Reveals a Non-redundant Role for PKN2 in Developmental Mesoderm Expansion.
Quétier I, Marshall JJT, Spencer-Dene B, Lachmann S, Casamassima A, Franco C, Escuin S, Worrall JT, Baskaran P, Rajeeve V, Howell M, Copp AJ, Stamp G, Rosewell I, Cutillas P, Gerhardt H, Parker PJ, Cameron AJM. Quétier I, et al. Among authors: rajeeve v. Cell Rep. 2016 Jan 26;14(3):440-448. doi: 10.1016/j.celrep.2015.12.049. Epub 2016 Jan 7. Cell Rep. 2016. PMID: 26774483 Free PMC article.
Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition.
Sciacovelli M, Gonçalves E, Johnson TI, Zecchini VR, da Costa AS, Gaude E, Drubbel AV, Theobald SJ, Abbo SR, Tran MG, Rajeeve V, Cardaci S, Foster S, Yun H, Cutillas P, Warren A, Gnanapragasam V, Gottlieb E, Franze K, Huntly B, Maher ER, Maxwell PH, Saez-Rodriguez J, Frezza C. Sciacovelli M, et al. Among authors: rajeeve v. Nature. 2016 Aug 31;537(7621):544-547. doi: 10.1038/nature19353. Nature. 2016. PMID: 27580029 Free PMC article.
Vps34 PI 3-kinase inactivation enhances insulin sensitivity through reprogramming of mitochondrial metabolism.
Bilanges B, Alliouachene S, Pearce W, Morelli D, Szabadkai G, Chung YL, Chicanne G, Valet C, Hill JM, Voshol PJ, Collinson L, Peddie C, Ali K, Ghazaly E, Rajeeve V, Trichas G, Srinivas S, Chaussade C, Salamon RS, Backer JM, Scudamore CL, Whitehead MA, Keaney EP, Murphy LO, Semple RK, Payrastre B, Tooze SA, Vanhaesebroeck B. Bilanges B, et al. Among authors: rajeeve v. Nat Commun. 2017 Nov 27;8(1):1804. doi: 10.1038/s41467-017-01969-4. Nat Commun. 2017. PMID: 29180704 Free PMC article.
44 results