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Page 1
Mutations in LZTR1 drive human disease by dysregulating RAS ubiquitination.
Steklov M, Pandolfi S, Baietti MF, Batiuk A, Carai P, Najm P, Zhang M, Jang H, Renzi F, Cai Y, Abbasi Asbagh L, Pastor T, De Troyer M, Simicek M, Radaelli E, Brems H, Legius E, Tavernier J, Gevaert K, Impens F, Messiaen L, Nussinov R, Heymans S, Eyckerman S, Sablina AA. Steklov M, et al. Among authors: simicek m. Science. 2018 Dec 7;362(6419):1177-1182. doi: 10.1126/science.aap7607. Epub 2018 Nov 15. Science. 2018. PMID: 30442762 Free PMC article.
OTUB1 triggers lung cancer development by inhibiting RAS monoubiquitination.
Baietti MF, Simicek M, Abbasi Asbagh L, Radaelli E, Lievens S, Crowther J, Steklov M, Aushev VN, Martínez García D, Tavernier J, Sablina AA. Baietti MF, et al. Among authors: simicek m. EMBO Mol Med. 2016 Mar 1;8(3):288-303. doi: 10.15252/emmm.201505972. EMBO Mol Med. 2016. PMID: 26881969 Free PMC article.
Mechanism of phospho-ubiquitin-induced PARKIN activation.
Wauer T, Simicek M, Schubert A, Komander D. Wauer T, et al. Among authors: simicek m. Nature. 2015 Aug 20;524(7565):370-4. doi: 10.1038/nature14879. Epub 2015 Jul 10. Nature. 2015. PMID: 26161729 Free PMC article.
Assembly and specific recognition of k29- and k33-linked polyubiquitin.
Michel MA, Elliott PR, Swatek KN, Simicek M, Pruneda JN, Wagstaff JL, Freund SM, Komander D. Michel MA, et al. Among authors: simicek m. Mol Cell. 2015 Apr 2;58(1):95-109. doi: 10.1016/j.molcel.2015.01.042. Epub 2015 Mar 5. Mol Cell. 2015. PMID: 25752577 Free PMC article.
Venetoclax: A new wave in hematooncology.
Mihalyova J, Jelinek T, Growkova K, Hrdinka M, Simicek M, Hajek R. Mihalyova J, et al. Among authors: simicek m. Exp Hematol. 2018 May;61:10-25. doi: 10.1016/j.exphem.2018.02.002. Epub 2018 Mar 2. Exp Hematol. 2018. PMID: 29477371 Free article. Review.
Mutation landscape of multiple myeloma measurable residual disease: identification of targets for precision medicine.
Zátopková M, Ševčíková T, Fanfani V, Chyra Z, Říhová L, Bezděková R, Žihala D, Growková K, Filipová J, Černá L, Broskevičova L, Kryukov F, Minařík J, Smejkalová J, Maisnar V, Harvanová Ĺ, Pour L, Jungova A, Popková T, Bago JR, Anilkumar Sithara A, Hrdinka M, Jelínek T, Šimíček M, Stracquadanio G, Hájek R. Zátopková M, et al. Among authors: simicek m. Blood Adv. 2022 Jan 25;6(2):368-372. doi: 10.1182/bloodadvances.2020003876. Blood Adv. 2022. PMID: 34500459 Free PMC article. No abstract available.
Single-agent venetoclax induces MRD-negative response in relapsed primary plasma cell leukemia with t(11;14).
Jelinek T, Mihalyova J, Kascak M, Duras J, Popkova T, Benkova K, Richterova P, Plonkova H, Zuchnicka J, Broskevicova L, Huvarova L, Cerna L, Growkova K, Simicek M, Havel M, Gumulec J, Navratil M, Koristek Z, Paiva B, Hajek R. Jelinek T, et al. Among authors: simicek m. Am J Hematol. 2019 Jan;94(1):E35-E37. doi: 10.1002/ajh.25331. Epub 2018 Nov 25. Am J Hematol. 2019. PMID: 30370955 Free article. No abstract available.
38 results