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Page 1
Somatic MED12 mutations in prostate cancer and uterine leiomyomas promote tumorigenesis through distinct mechanisms.
Kämpjärvi K, Kim NH, Keskitalo S, Clark AD, von Nandelstadh P, Turunen M, Heikkinen T, Park MJ, Mäkinen N, Kivinummi K, Lintula S, Hotakainen K, Nevanlinna H, Hokland P, Böhling T, Bützow R, Böhm J, Mecklin JP, Järvinen H, Kontro M, Visakorpi T, Taipale J, Varjosalo M, Boyer TG, Vahteristo P. Kämpjärvi K, et al. Among authors: von nandelstadh p. Prostate. 2016 Jan;76(1):22-31. doi: 10.1002/pros.23092. Epub 2015 Sep 18. Prostate. 2016. PMID: 26383637
Identification of 33 candidate oncogenes by screening for base-specific mutations.
Tuupanen S, Hänninen UA, Kondelin J, von Nandelstadh P, Cajuso T, Gylfe AE, Katainen R, Tanskanen T, Ristolainen H, Böhm J, Mecklin JP, Järvinen H, Renkonen-Sinisalo L, Andersen CL, Taipale M, Taipale J, Vahteristo P, Lehti K, Pitkänen E, Aaltonen LA. Tuupanen S, et al. Among authors: von nandelstadh p. Br J Cancer. 2014 Oct 14;111(8):1657-62. doi: 10.1038/bjc.2014.429. Epub 2014 Aug 12. Br J Cancer. 2014. PMID: 25117815 Free PMC article.
Somatic MED12 Nonsense Mutation Escapes mRNA Decay and Reveals a Motif Required for Nuclear Entry.
Heikkinen T, Kämpjärvi K, Keskitalo S, von Nandelstadh P, Liu X, Rantanen V, Pitkänen E, Kinnunen M, Kuusanmäki H, Kontro M, Turunen M, Mäkinen N, Taipale J, Heckman C, Lehti K, Mustjoki S, Varjosalo M, Vahteristo P. Heikkinen T, et al. Among authors: von nandelstadh p. Hum Mutat. 2017 Mar;38(3):269-274. doi: 10.1002/humu.23157. Epub 2017 Jan 11. Hum Mutat. 2017. PMID: 28054750
Gremlin-1 is a key regulator of the invasive cell phenotype in mesothelioma.
Yin M, Tissari M, Tamminen J, Ylivinkka I, Rönty M, von Nandelstadh P, Lehti K, Hyytiäinen M, Myllärniemi M, Koli K. Yin M, et al. Among authors: von nandelstadh p. Oncotarget. 2017 Oct 6;8(58):98280-98297. doi: 10.18632/oncotarget.21550. eCollection 2017 Nov 17. Oncotarget. 2017. PMID: 29228689 Free PMC article.
FGFR4 phosphorylates MST1 to confer breast cancer cells resistance to MST1/2-dependent apoptosis.
Turunen SP, von Nandelstadh P, Öhman T, Gucciardo E, Seashore-Ludlow B, Martins B, Rantanen V, Li H, Höpfner K, Östling P, Varjosalo M, Lehti K. Turunen SP, et al. Among authors: von nandelstadh p. Cell Death Differ. 2019 Dec;26(12):2577-2593. doi: 10.1038/s41418-019-0321-x. Epub 2019 Mar 22. Cell Death Differ. 2019. PMID: 30903103 Free PMC article.
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