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Role of humoral immunity against hepatitis B virus core antigen in the pathogenesis of acute liver failure.
Chen Z, Diaz G, Pollicino T, Zhao H, Engle RE, Schuck P, Shen CH, Zamboni F, Long Z, Kabat J, De Battista D, Bock KW, Moore IN, Wollenberg K, Soto C, Govindarajan S, Kwong PD, Kleiner DE, Purcell RH, Farci P. Chen Z, et al. Among authors: govindarajan s. Proc Natl Acad Sci U S A. 2018 Nov 27;115(48):E11369-E11378. doi: 10.1073/pnas.1809028115. Epub 2018 Nov 12. Proc Natl Acad Sci U S A. 2018. PMID: 30420516 Free PMC article.
B cell gene signature with massive intrahepatic production of antibodies to hepatitis B core antigen in hepatitis B virus-associated acute liver failure.
Farci P, Diaz G, Chen Z, Govindarajan S, Tice A, Agulto L, Pittaluga S, Boon D, Yu C, Engle RE, Haas M, Simon R, Purcell RH, Zamboni F. Farci P, et al. Among authors: govindarajan s. Proc Natl Acad Sci U S A. 2010 May 11;107(19):8766-71. doi: 10.1073/pnas.1003854107. Epub 2010 Apr 26. Proc Natl Acad Sci U S A. 2010. PMID: 20421498 Free PMC article.
Viral expression and molecular profiling in liver tissue versus microdissected hepatocytes in hepatitis B virus-associated hepatocellular carcinoma.
Melis M, Diaz G, Kleiner DE, Zamboni F, Kabat J, Lai J, Mogavero G, Tice A, Engle RE, Becker S, Brown CR, Hanson JC, Rodriguez-Canales J, Emmert-Buck M, Govindarajan S, Kew M, Farci P. Melis M, et al. Among authors: govindarajan s. J Transl Med. 2014 Aug 21;12:230. doi: 10.1186/s12967-014-0230-1. J Transl Med. 2014. PMID: 25141867 Free PMC article.
Molecular Signature and Mechanisms of Hepatitis D Virus-Associated Hepatocellular Carcinoma.
Diaz G, Engle RE, Tice A, Melis M, Montenegro S, Rodriguez-Canales J, Hanson J, Emmert-Buck MR, Bock KW, Moore IN, Zamboni F, Govindarajan S, Kleiner DE, Farci P. Diaz G, et al. Among authors: govindarajan s. Mol Cancer Res. 2018 Sep;16(9):1406-1419. doi: 10.1158/1541-7786.MCR-18-0012. Epub 2018 Jun 1. Mol Cancer Res. 2018. PMID: 29858376 Free PMC article.
Distinct disease features in chimpanzees infected with a precore HBV mutant associated with acute liver failure in humans.
Chen Z, Engle RE, Shen CH, Zhao H, Schuck PW, Danoff EJ, Nguyen H, Nishimura N, Bock KW, Moore IN, Kwong PD, Purcell RH, Govindarajan S, Farci P. Chen Z, et al. Among authors: govindarajan s. PLoS Pathog. 2020 Aug 31;16(8):e1008793. doi: 10.1371/journal.ppat.1008793. eCollection 2020 Aug. PLoS Pathog. 2020. PMID: 32866189 Free PMC article.
Chitinase 3-like 1 is a profibrogenic factor overexpressed in the aging liver and in patients with liver cirrhosis.
Nishimura N, De Battista D, McGivern DR, Engle RE, Tice A, Fares-Gusmao R, Kabat J, Pomerenke A, Nguyen H, Sato S, Bock KW, Moore IN, Kleiner DE, Zamboni F, Alter HJ, Govindarajan S, Farci P. Nishimura N, et al. Among authors: govindarajan s. Proc Natl Acad Sci U S A. 2021 Apr 27;118(17):e2019633118. doi: 10.1073/pnas.2019633118. Proc Natl Acad Sci U S A. 2021. PMID: 33888584 Free PMC article.
Mutations that permit efficient replication of hepatitis C virus RNA in Huh-7 cells prevent productive replication in chimpanzees.
Bukh J, Pietschmann T, Lohmann V, Krieger N, Faulk K, Engle RE, Govindarajan S, Shapiro M, St Claire M, Bartenschlager R. Bukh J, et al. Among authors: govindarajan s. Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):14416-21. doi: 10.1073/pnas.212532699. Epub 2002 Oct 21. Proc Natl Acad Sci U S A. 2002. PMID: 12391335 Free PMC article.
441 results