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The calcium sensitizer drug MCI-154 binds the structural C-terminal domain of cardiac troponin C.
Biochem Biophys Rep. 2018 Nov 1;16:145-151. doi: 10.1016/j.bbrep.2018.10.012. eCollection 2018 Dec.
Biochem Biophys Rep. 2018.
PMID: 30417133
Free PMC article.
Structures reveal details of small molecule binding to cardiac troponin.
Cai F, Li MX, Pineda-Sanabria SE, Gelozia S, Lindert S, West F, Sykes BD, Hwang PM.
Cai F, et al. Among authors: gelozia s.
J Mol Cell Cardiol. 2016 Dec;101:134-144. doi: 10.1016/j.yjmcc.2016.10.016. Epub 2016 Nov 5.
J Mol Cell Cardiol. 2016.
PMID: 27825981
Free PMC article.
Review.
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One-Pot Generation of Bicyclo[3.1.0]hexanols and Cyclohexanones by Double Interrupted Nazarov Reactions.
Gelozia S, Kwon Y, McDonald R, West FG.
Gelozia S, et al.
Chemistry. 2018 Apr 20;24(23):6052-6056. doi: 10.1002/chem.201800758. Epub 2018 Mar 26.
Chemistry. 2018.
PMID: 29444379
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