Chiosis G - Search Results

1

Chaperome heterogeneity and its implications for cancer study and treatment.

Wang T, Rodina A, Dunphy MP, Corben A, Modi S, Guzman ML, Gewirth DT, Chiosis G. Wang T, et al. Among authors: chiosis g. J Biol Chem. 2019 Feb 8;294(6):2162-2179. doi: 10.1074/jbc.REV118.002811. Epub 2018 Nov 8. J Biol Chem. 2019. PMID: 30409908 Free PMC article. Review.

2

Akt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 function.

Basso AD, Solit DB, Chiosis G, Giri B, Tsichlis P, Rosen N. Basso AD, et al. Among authors: chiosis g. J Biol Chem. 2002 Oct 18;277(42):39858-66. doi: 10.1074/jbc.M206322200. Epub 2002 Aug 9. J Biol Chem. 2002. PMID: 12176997 Free article.

3

Targeting wide-range oncogenic transformation via PU24FCl, a specific inhibitor of tumor Hsp90.

Vilenchik M, Solit D, Basso A, Huezo H, Lucas B, He H, Rosen N, Spampinato C, Modrich P, Chiosis G. Vilenchik M, et al. Among authors: chiosis g. Chem Biol. 2004 Jun;11(6):787-97. doi: 10.1016/j.chembiol.2004.04.008. Chem Biol. 2004. PMID: 15217612

4

Identification of potent water soluble purine-scaffold inhibitors of the heat shock protein 90.

He H, Zatorska D, Kim J, Aguirre J, Llauger L, She Y, Wu N, Immormino RM, Gewirth DT, Chiosis G. He H, et al. Among authors: chiosis g. J Med Chem. 2006 Jan 12;49(1):381-90. doi: 10.1021/jm0508078. J Med Chem. 2006. PMID: 16392823

5

Targeting chaperones in transformed systems--a focus on Hsp90 and cancer.

Chiosis G. Chiosis G. Expert Opin Ther Targets. 2006 Feb;10(1):37-50. doi: 10.1517/14728222.10.1.37. Expert Opin Ther Targets. 2006. PMID: 16441227 Review.

6

Emerging Hsp90 inhibitors: from discovery to clinic.

Chiosis G, Rodina A, Moulick K. Chiosis G, et al. Anticancer Agents Med Chem. 2006 Jan;6(1):1-8. doi: 10.2174/187152006774755483. Anticancer Agents Med Chem. 2006. PMID: 16475922 Review.

7

Structural and quantum chemical studies of 8-aryl-sulfanyl adenine class Hsp90 inhibitors.

Immormino RM, Kang Y, Chiosis G, Gewirth DT. Immormino RM, et al. Among authors: chiosis g. J Med Chem. 2006 Aug 10;49(16):4953-60. doi: 10.1021/jm060297x. J Med Chem. 2006. PMID: 16884307

8

Selective compounds define Hsp90 as a major inhibitor of apoptosis in small-cell lung cancer.

Rodina A, Vilenchik M, Moulick K, Aguirre J, Kim J, Chiang A, Litz J, Clement CC, Kang Y, She Y, Wu N, Felts S, Wipf P, Massague J, Jiang X, Brodsky JL, Krystal GW, Chiosis G. Rodina A, et al. Among authors: chiosis g. Nat Chem Biol. 2007 Aug;3(8):498-507. doi: 10.1038/nchembio.2007.10. Epub 2007 Jul 1. Nat Chem Biol. 2007. PMID: 17603540

9

High-throughput screening fluorescence polarization assay for tumor-specific Hsp90.

Du Y, Moulick K, Rodina A, Aguirre J, Felts S, Dingledine R, Fu H, Chiosis G. Du Y, et al. Among authors: chiosis g. J Biomol Screen. 2007 Oct;12(7):915-24. doi: 10.1177/1087057107306067. J Biomol Screen. 2007. PMID: 17942784

10

Heat shock protein 90: translation from cancer to Alzheimer's disease treatment?

Luo W, Rodina A, Chiosis G. Luo W, et al. Among authors: chiosis g. BMC Neurosci. 2008 Dec 3;9 Suppl 2(Suppl 2):S7. doi: 10.1186/1471-2202-9-S2-S7. BMC Neurosci. 2008. PMID: 19090995 Free PMC article. Review.

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