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A Proposed Roadmap for Parkinson's Disease Proof of Concept Clinical Trials Investigating Compounds Targeting Alpha-Synuclein.
Merchant KM, Cedarbaum JM, Brundin P, Dave KD, Eberling J, Espay AJ, Hutten SJ, Javidnia M, Luthman J, Maetzler W, Menalled L, Reimer AN, Stoessl AJ, Weiner DM; The Michael J. Fox Foundation Alpha Synuclein Clinical Path Working Group. Merchant KM, et al. Among authors: dave kd. J Parkinsons Dis. 2019;9(1):31-61. doi: 10.3233/JPD-181471. J Parkinsons Dis. 2019. PMID: 30400107 Free PMC article.
The Systemic Synuclein Sampling Study: toward a biomarker for Parkinson's disease.
Visanji NP, Mollenhauer B, Beach TG, Adler CH, Coffey CS, Kopil CM, Dave KD, Foroud T, Chahine L, Jennings D; Systemic Synuclein Sampling Study (S4). Visanji NP, et al. Among authors: dave kd. Biomark Med. 2017 Apr;11(4):359-368. doi: 10.2217/bmm-2016-0366. Epub 2017 Mar 29. Biomark Med. 2017. PMID: 28353371
Therapeutic approaches to target alpha-synuclein pathology.
Brundin P, Dave KD, Kordower JH. Brundin P, et al. Among authors: dave kd. Exp Neurol. 2017 Dec;298(Pt B):225-235. doi: 10.1016/j.expneurol.2017.10.003. Epub 2017 Oct 4. Exp Neurol. 2017. PMID: 28987463 Free PMC article. Review.
Antibody-based methods for the measurement of α-synuclein concentration in human cerebrospinal fluid - method comparison and round robin study.
Mollenhauer B, Bowman FD, Drake D, Duong J, Blennow K, El-Agnaf O, Shaw LM, Masucci J, Taylor P, Umek RM, Dunty JM, Smith CL, Stoops E, Vanderstichele H, Schmid AW, Moniatte M, Zhang J, Kruse N, Lashuel HA, Teunissen C, Schubert T, Dave KD, Hutten SJ, Zetterberg H. Mollenhauer B, et al. Among authors: dave kd. J Neurochem. 2019 Apr;149(1):126-138. doi: 10.1111/jnc.14569. Epub 2018 Nov 13. J Neurochem. 2019. PMID: 30125936 Free PMC article.
Feasibility and Safety of Multicenter Tissue and Biofluid Sampling for α-Synuclein in Parkinson's Disease: The Systemic Synuclein Sampling Study (S4).
Chahine LM, Beach TG, Seedorff N, Caspell-Garcia C, Coffey CS, Brumm M, Adler CH, Serrano GE, Linder C, Mosovsky S, Foroud T, Riss H, Ecklund D, Seibyl J, Jennings D, Arnedo V, Riley L, Dave KD, Mollenhauer B; Systemic sSynuclein Sampling study. Chahine LM, et al. Among authors: dave kd. J Parkinsons Dis. 2018;8(4):517-527. doi: 10.3233/JPD-181434. J Parkinsons Dis. 2018. PMID: 30248065 Free PMC article.
Antemortem detection of Parkinson's disease pathology in peripheral biopsies using artificial intelligence.
Signaevsky M, Marami B, Prastawa M, Tabish N, Iida MA, Zhang XF, Sawyer M, Duran I, Koenigsberg DG, Bryce CH, Chahine LM, Mollenhauer B, Mosovsky S, Riley L, Dave KD, Eberling J, Coffey CS, Adler CH, Serrano GE, White CL 3rd, Koll J, Fernandez G, Zeineh J, Cordon-Cardo C, Beach TG, Crary JF. Signaevsky M, et al. Among authors: dave kd. Acta Neuropathol Commun. 2022 Feb 14;10(1):21. doi: 10.1186/s40478-022-01318-7. Acta Neuropathol Commun. 2022. PMID: 35164870 Free PMC article.
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